Neurog3 - neurogenin 3 Gene

Also Known as Ngn3; Relax

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 60329

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and double-stranded DNA binding activity. Involved in central nervous system development; positive regulation of neuron differentiation; and regulation of transcription, DNA-templated. Located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in congenital malabsorptive diarrhea 4; glucose intolerance; and type 2 diabetes mellitus. Orthologous to human NEUROG3 (neurogenin 3). [provided by Alliance of Genome Resources, Apr 2022]

Neurog3 Products (1)

mRNA Protein Name
NM_021700.2 NP_067732.1 neurogenin-3

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
9130143 RGD
enables double-stranded DNA binding IDA
IDA: Inferred from direct assay
9130143 RGD
Biological Process GO Annotation Evidence References Source
involved in forebrain development IEP
IEP: Inferred from expression pattern
9130143 RGD
involved in hindbrain development IEP
IEP: Inferred from expression pattern
9130143 RGD
involved in positive regulation of cell differentiation IEP
IEP: Inferred from expression pattern
16514419 RGD
involved in positive regulation of neuron differentiation IMP
IMP: Inferred from mutant phenotype
9238023 RGD
involved in regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
9130143 RGD
involved in spinal cord development IEP
IEP: Inferred from expression pattern
9130143 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

neurogenin-3

  • transcriptional regulator, Relax

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09230 NEUROG3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174570 Human NEUROG3 mRNA / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Neurog3 NCBI NCBI:50674