Kcnt1 - potassium sodium-activated channel subfamily T member 1 Gene

Also Known as Slack; rSlo2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 60444

Summary

Enables Potassium Channel activity. Involved in potassium ion transport. Is integral component of membrane. Human ortholog(s) of this gene implicated in autosomal dominant nocturnal frontal lobe epilepsy 5 and developmental and epileptic encephalopathy 14. Orthologous to human KCNT1 (potassium sodium-activated channel subfamily T member 1). [provided by Alliance of Genome Resources, Apr 2022]

Kcnt1 Products (2)

mRNA Protein Name
NM_001413123.1 NP_001400052.1 potassium channel subfamily T member 1 isoform 2
NM_021853.2 NP_068625.2 potassium channel subfamily T member 1 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables chloride-activated potassium channel activity IDA
IDA: Inferred from direct assay
14684870 RGD
enables intracellular sodium-activated potassium channel activity IDA
IDA: Inferred from direct assay
14684870 RGD
enables potassium channel activity IDA
IDA: Inferred from direct assay
12628167 RGD
Biological Process GO Annotation Evidence References Source
involved in potassium ion transmembrane transport IDA
IDA: Inferred from direct assay
14684870 RGD
involved in potassium ion transport IDA
IDA: Inferred from direct assay
12628167 RGD
Cellular Component GO Annotation Evidence References Source
located in plasma membrane IDA
IDA: Inferred from direct assay
12442315 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

potassium channel subfamily T member 1

  • potassium channel subunit (Slack)

  • potassium channel, sodium-activated subfamily T, member 1

  • potassium channel, subfamily T, member 1

  • sequence like a calcium-activated potassium channel subunit

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-162549 CPK20 Inhibitor 99.67% Unkown
HY-159958 KNa1.1-IN-2 Antagonist / Unkown
HY-175335 KCNT1-IN-1 Inhibitor 99.18% Unkown
HY-179093 KCNT1-IN-3 Inhibitor / Unkown
HY-RS07181 KCNT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-175336 KCNT1-IN-2 Inhibitor / Unkown
HY-P0058S Pramlintide-(Ala-13C3,15N) / Unkown
HY-RS22590 Kcnt1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kcnt1 NCBI NCBI:57582