2. Gene
  3. Kcnt1 - potassium sodium-activated channel subfamily T member 1 Gene

Kcnt1 - potassium sodium-activated channel subfamily T member 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Slack; rSlo2

Gene ID: 60444 | Gene type: protein coding

About Kcnt1

Summary

Enables Potassium Channel activity. Involved in potassium ion transport. Is integral component of membrane. Human ortholog(s) of this gene implicated in autosomal dominant nocturnal frontal lobe epilepsy 5 and developmental and epileptic encephalopathy 14. Orthologous to human KCNT1 (potassium sodium-activated channel subfamily T member 1). [provided by Alliance of Genome Resources, Apr 2022]

Kcnt1 Products(2)

mRNA Protein Name
NM_001413123.1 NP_001400052.1 potassium channel subfamily T member 1 isoform 2
NM_021853.2 NP_068625.2 potassium channel subfamily T member 1 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables chloride-activated potassium channel activity IDA
IDA: Inferred from direct assay
14684870 RGD
enables intracellular sodium-activated potassium channel activity IDA
IDA: Inferred from direct assay
14684870 RGD
enables potassium channel activity IDA
IDA: Inferred from direct assay
12628167 RGD
Biological Process GO Annotation Evidence Reference Source
involved in potassium ion transmembrane transport IDA
IDA: Inferred from direct assay
14684870 RGD
involved in potassium ion transport IDA
IDA: Inferred from direct assay
12628167 RGD
Cellular Component GO Annotation Evidence Reference Source
located in plasma membrane IDA
IDA: Inferred from direct assay
12442315 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

potassium channel subfamily T member 1

potassium channel subunit (Slack)

potassium channel, sodium-activated subfamily T, member 1

potassium channel, subfamily T, member 1

sequence like a calcium-activated potassium channel subunit

Related Agents

Pre-clinical Phase
Bioactive Molecules (8)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-162549 CPK20 Inhibitor 99.67% Unkown
HY-159958 KNa1.1-IN-2 Antagonist / Unkown
HY-175335 KCNT1-IN-1 Inhibitor / Unkown
HY-179093 KCNT1-IN-3 Inhibitor / Unkown
HY-RS07181 KCNT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-175336 KCNT1-IN-2 Inhibitor / Unkown
HY-P0058S Pramlintide-(Ala-13C3,15N) / Unkown
HY-RS22590 Kcnt1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kcnt1 NCBI NCBI:57582