WO662
Based on 1 Customer Validation
WO662 (compound I-1a) is a KCNT1 inhibitor with an IC50 ≤ 250 nM. WO662 can be used in the research of neurological diseases.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity : 99.18%
- CAS No.: 3087554-10-4
- 화학식: C18H14F6N6O
- 분자량:444.33
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보관:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
제품 설명
Chemical Information
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CAS No. 3087554-10-4
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Appearance Solid
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분자량 444.33
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화학식 C18H14F6N6O
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Color White to off-white
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SMILES
O=C(C1=CC(C(F)(F)F)=NN1C)N[C@@H]2C3=CN(C4=CC=NC(C(F)(F)F)=C4)N=C3CC2
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Synonyms
KCNT1-IN-1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
용액&용해도
In Vitro:
DMSO : 12.5 mg/mL (28.13 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
순도&문서
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.2506 mL | 11.2529 mL | 22.5058 mL | 56.2645 mL |
| 5 mM | 0.4501 mL | 2.2506 mL | 4.5012 mL | 11.2529 mL | |
| 10 mM | 0.2251 mL | 1.1253 mL | 2.2506 mL | 5.6264 mL | |
| 15 mM | 0.1500 mL | 0.7502 mL | 1.5004 mL | 3.7510 mL | |
| 20 mM | 0.1125 mL | 0.5626 mL | 1.1253 mL | 2.8132 mL | |
| 25 mM | 0.0900 mL | 0.4501 mL | 0.9002 mL | 2.2506 mL |