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KNa1.1-IN-2

KNa1.1-IN-2 (Compound Z05) is a selective KNa1.1 channel inhibitor with blood-brain barrier penetration, particularly effective against the hERG channel. KNa1.1-IN-2 works by binding to the KNa1.1 channel and blocking the channel activity induced by Gain-of-function (GOF) mutations, effectively intervening in KCNT1-related epilepsy. Additionally, KNa1.1-IN-2 inhibits the GOF mutant Y796H. KNa1.1-IN-2 holds promise for research into KCNT1-related epilepsy disorders.

For research use only. We do not sell to patients.

  • CAS No.: 3037315-44-6
  • Formula: C24H27NO
  • Molecular Weight:345.48
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • KNa1.1-IN-2 Chemical Structure
    KNa1.1-IN-2 Chemical Structure
CAS No.: 3037315-44-6
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  • KNa1.1-IN-2 Chemical Structure
    KNa1.1-IN-2 Chemical Structure
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  • KNa1.1-IN-2