Crx - cone-rod homeobox Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 60446

Summary

Enables DNA binding activity. Involved in circadian rhythm and positive regulation of photoreceptor cell differentiation. Located in nucleus. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 7 and cone-rod dystrophy 2. Orthologous to human CRX (cone-rod homeobox). [provided by Alliance of Genome Resources, Apr 2022]

Crx Products (1)

mRNA Protein Name
NM_021855.2 NP_068627.2 cone-rod homeobox protein

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Références Source
enables DNA binding IDA
IDA: Inferred from direct assay
9465110 RGD
Biological Process GO Annotation Evidence Références Source
involved in circadian rhythm IEP
IEP: Inferred from expression pattern
9465110 RGD
involved in positive regulation of photoreceptor cell differentiation IEP
IEP: Inferred from expression pattern
16799048 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cone-rod homeobox protein

  • cone-rod homeobox containing

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Nom du produit Effect
Pureté Phase
HY-111792 GSK1795091 Agonist 94.48% Phase 1

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-153759 CRX000227 Modulator 95.0% Unkown
HY-155801 CRX 527 / Unkown
HY-RS03203 CRX Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-118984 CRX-526 Antagonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Crx NCBI NCBI:1406