2. Gene
  3. Crx - cone-rod homeobox Gene

Crx - cone-rod homeobox Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 60446 | Gene type: protein coding

About Crx

Summary

Enables DNA binding activity. Involved in circadian rhythm and positive regulation of photoreceptor cell differentiation. Located in nucleus. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 7 and cone-rod dystrophy 2. Orthologous to human CRX (cone-rod homeobox). [provided by Alliance of Genome Resources, Apr 2022]

Crx Products(1)

mRNA Protein Name
NM_021855.2 NP_068627.2 cone-rod homeobox protein
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables DNA binding IDA
IDA: Inferred from direct assay
9465110 RGD
Biological Process GO Annotation Evidence Reference Source
involved in circadian rhythm IEP
IEP: Inferred from expression pattern
9465110 RGD
involved in positive regulation of photoreceptor cell differentiation IEP
IEP: Inferred from expression pattern
16799048 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cone-rod homeobox protein

cone-rod homeobox containing

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-111792 GSK1795091 Agonist 94.48% Phase 1
Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-153759 CRX000227 Modulator 95.0% Unkown
HY-155801 CRX 527 / Unkown
HY-RS03203 CRX Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-118984 CRX-526 Antagonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Crx NCBI NCBI:1406