1. Gene
  2. S100A3 - S100 calcium binding protein A3 Gene

S100A3 - S100 calcium binding protein A3 Gene

Homo sapiens

Also known as S100E

Gene ID: 6274 | Gene type: protein coding

About S100A3

Cytogenetic location: 1q21.3 Genomic coordinates (GRCh38): 1:153,547,329-153,549,258 (from NCBI)

This gene has 2 transcripts (splice variants), 337 orthologues and 21 paralogues. Biased expression in lung (RPKM 11.5), skin (RPKM 3.7) and 10 other tissues.

Summary

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein has the highest content of cysteines of all S100 proteins, has a high affinity for Zinc, and is highly expressed in human hair cuticle. The precise function of this protein is unknown. [provided by RefSeq, Jul 2008]

S100A3 Products(1)

mRNA Protein Name
NM_002960.2 NP_002951.1 protein S100-A3

S100A3 Protein Structure

S_100

S_100: S-100/ICaBP type calcium binding domain (5 - 46)

  • 0
  • 101 a.a.
Protein Preferred Names Protein Names

protein S100-A3

Recombinant S100A3 Proteins

Cat. No. Product Name Accession Purity
HY-P76585 S100A3 Protein, Human (His-MBP) P33764 (M1-Q101) ≥95%

Related Diseases

Diseases Alias
Pilomatrixoma

Pilomatricoma

PTR

Epithelioma Calcificans Of Malherbe

Benign Pilomatricoma

Calcifying Epithelioma Of Malherbe

Pilomatricoma, Somatic

Benign Pilomatrixoma

Malherbe Calcifying Epithelioma

Classic Pulmonary Blastoma

Biphasic Pulmonary Blastoma

Epidermoid Cysts

Epidermoid Cyst

Sebaceous Cyst

Epidermal Inclusion Cyst

Epidermal Cyst

Anaplastic Astrocytoma

Grade Iii Astrocytoma

Astrocytoma, Anaplastic

Grade Iii Astrocytic Tumor

Psoriasis 7

PSORS7

Psoriasis 7, Susceptibility To

Psoriasis Susceptibility 7

Psoriasis

Psoriasis Vulgaris

Pv

Hypotrichosis 2

HYPT2

Hypotrichosis Simplex Of The Scalp 1

Htss1

Htss

Hypotrichosis, Spanish Type

Spanish Type Hypotrichosis

Hypotrichosis Spanish Type

Hypotrichosis, Type 2

Hypotrichosis Simplex Of Scalp

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Rattus norvegicus S100A3 RGD RGD:620260
Macaca mulatta S100A3 VGNC VGNC:76957
Mus musculus S100A3 MGD MGI:1338849
Bos taurus S100A3 VGNC VGNC:34243
Canis familiaris S100A3 VGNC VGNC:45829
Others S100A3 NCBI