S100Z - S100 calcium binding protein Z Gene

Also Known as Gm625; S100-zeta

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 170591

About S100Z

Cytogenetic location: 5q13.3 Genomic coordinates (GRCh38): 5:76,850,014-76,952,953 (from NCBI)

This gene has 3 transcripts (splice variants), 184 orthologues and 21 paralogues. Low expression observed in reference dataset.

Summary

Members of the S100 protein family contain 2 calcium-binding EF-hands and exhibit cell-type specific expression patterns. For additional background information on S100 proteins, see MIM 114085.[supplied by OMIM, Mar 2008]

S100Z Products (1)

mRNA Protein Name
NM_130772.4 NP_570128.2 protein S100-Z

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables calcium ion binding IDA
IDA: Inferred from direct assay
11747429 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
11747429 GOA
enables protein homodimerization activity IDA
IDA: Inferred from direct assay
11747429 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

S100Z Protein Structure

S_100

S_100: S-100/ICaBP type calcium binding domain (5 - 46)

  • 0
  • 99 a.a.
Protein Preferred Names Protein Names

protein S100-Z

  • S100 calcium binding protein, zeta

S100Z Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
S100Z Q8WXG8 S100B Homo sapiens P04271
Y2H Array
32296183
Intra
S100Z Q8WXG8 S100B Homo sapiens P04271
Y2H Prey Pooling
32296183
Intra
S100Z Q8WXG8 RBM48 Homo sapiens Q5RL73
Y2H Array
32296183
Intra
S100Z Q8WXG8 RBM48 Homo sapiens Q5RL73
Y2H Prey Pooling
32296183
Intra
S100Z Q8WXG8 S100A10 Homo sapiens P60903
Y2H Prey Pooling
32296183
Intra
S100Z Q8WXG8 S100A10 Homo sapiens P60903
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Pulmonary Systemic Sclerosis

  • Lung Disease With Systemic Sclerosis

  • Lung Involvement In Systemic Sclerosis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12390 S100Z Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus S100Z RGD RGD:1562902
Mus musculus S100Z MGD MGI:2685471
Felis catus S100Z VGNC VGNC:102311
Bos taurus S100Z VGNC VGNC:34251
Others S100Z NCBI