Dhcr7 - 7-dehydrocholesterol reductase Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 64191

Summary

Enables 7-dehydrocholesterol reductase activity. Involved in Cholesterol biosynthetic process and regulation of Cholesterol biosynthetic process. Located in intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in Smith-Lemli-Opitz syndrome. Orthologous to human DHCR7 (7-dehydrocholesterol reductase). [provided by Alliance of Genome Resources, Apr 2022]

Dhcr7 Products (1)

mRNA Protein Name
NM_022389.3 NP_071784.1 7-dehydrocholesterol reductase

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables 7-dehydrocholesterol reductase activity IMP
IMP: Inferred from mutant phenotype
9831636 RGD
Biological Process GO Annotation Evidence References Source
involved in cholesterol biosynthetic process IDA
IDA: Inferred from direct assay
10329655 RGD
involved in cholesterol biosynthetic process IMP
IMP: Inferred from mutant phenotype
9831636 RGD
involved in regulation of cholesterol biosynthetic process IDA
IDA: Inferred from direct assay
10329655 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

7-dehydrocholesterol reductase

  • 7-DHC reductase

  • sterol Delta(7)-reductase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-107420 AY 9944 99.67% Unkown
HY-164561 TASIN-30 99.96% Unkown
HY-Y0889 1-(2,3-Dichlorphenyl)piperazine 99.38% Unkown
HY-Y0889A 1-(2,3-Dichlorphenyl)piperazine hydrochloride 99.98% Unkown
HY-RS03727 DHCR7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-107420S AY 9944-d8 / Unkown
HY-RS17300 Dhcr7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23755 Dhcr7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dhcr7 NCBI NCBI:1717