LGALS7B - galectin 7B Gene

Also Known as PI7; GAL7; Gal-7; HKL-14; LGALS7

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 653499

About LGALS7B

Cytogenetic location: 19q13.2 Genomic coordinates (GRCh38): 19:38,789,200-38,791,754 (from NCBI)

This gene has 2 transcripts (splice variants), 1 gene allele, 328 orthologues and 16 paralogues. Restricted expression toward skin (RPKM 506.8).

Summary

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridization studies indicate that this lectin is specifically expressed in keratinocytes and found mainly in stratified squamous epithelium. A duplicate copy of this gene (GeneID:3963) is found adjacent to, but on the opposite strand on chromosome 19. [provided by RefSeq, Jul 2008]

LGALS7B Products (1)

mRNA Protein Name
NM_001042507.4 NP_001035972.1 galectin-7
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

LGALS7B Protein Structure

Gal-bind_lectin

Gal-bind_lectin: Galactoside-binding lectin (7 - 134)

  • 0
  • 100
  • 136 a.a.
Protein Preferred Names Protein Names

galectin-7

  • keratinocyte lectin 14

Recombinant LGALS7B Proteins

Cat. No. Product Name Accession Purity
HY-P70358 Galectin-7/LGALS7 Protein, Human P47929 (M1-F136) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P73071 Galectin-7/LGALS7 Protein, Human (GST) P47929 (S2-F136) ≥ 90%, as determined by reducing SDS-PAGE.
HY-P700080AF Animal-Free Galectin-7/LGALS7 Protein, Human (His) P47929 (S2-F136) ≥ 95%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Esophageal Basaloid Squamous Cell Carcinoma
  • Basaloid Squamous Carcinoma Of Esophagus

  • Esophageal Basaloid Carcinoma

Galactosemia I
  • Galactosemia

  • Galt Deficiency

  • Classic Galactosemia

  • Galactose-1-Phosphate Uridylyltransferase Deficiency

  • Galactose-1-Phosphate Uridyltransferase Deficiency

  • GALAC1

  • Galactosemia, Classic

  • Galactosemia Type 1

  • Galactosemias

  • Classical Galactosemia

  • Galactosaemia

  • Galactose Intolerance

  • Epimerase Deficiency Galactosemia

  • Galactokinase Deficiency Disease

  • Galactose Epimerase Deficiency

  • Galactose-1-Phosphate Uridyl-Transferase Deficiency Disease

  • Gale Deficiency

  • Galk Deficiency

  • Udp-Galactose-4-Epimerase Deficiency Disease

  • Utp Hexose-1-Phosphate Uridylyltransferase Deficiency

  • Galactosemia 1

  • Galactosemia, Duarte Variant

  • Deficiency Of Galactokinase

  • Udpglucose 4-Epimerase Deficiency Disease

  • Classical Galactosaemia

  • Galput Deficiency - [Galactose-4-Phosphate Uridyltransferase] Deficiency

  • Classic Galactosaemia

  • Deficiency Of Hexose-1-Phosphate Uridylyltransferase

  • Deficiency Of Udpglucose-Hexose-1-Phosphate Uridylyltransferase

  • Deficiency Of Galactose-1-Phosphate Uridylyltransferase

  • Galactose-1-Phosphate Uridyl Transferase Deficiency

  • Transferase Deficiency Galactosemia

  • Deficiency Of Uridyl Transferase

  • Deficiency Of Utp-Hexose-1-Phosphate Uridylyltransferase

  • Utp-Hexose-1-Phosphate Uridyltransferase Deficiency

Bladder Squamous Cell Carcinoma
  • Squamous Cell Carcinoma Of Bladder

  • Epidermoid Carcinoma Of The Urinary Bladder

  • Carcinoma Squamous Cell Bladder

Amyloid Tumor
  • Amyloid Neoplasm

  • Amyloid Tumour

Verruciform Xanthoma Of Skin
  • Verruciform Xanthoma

  • Cutaneous Verruciform Xanthoma

Fetal Adenoma
  • Microfollicular Adenoma

Uterus Carcinoma In Situ
Cervix Uteri Carcinoma In Situ
  • Carcinoma In Situ Of Cervix

  • Carcinoma In Situ Of Uterine Cervix

  • Cervical Intraepithelial Neoplasia

  • Carcinoma Of Cervix Stage 0

  • Cervical Intraepithelial Neoplasia Grade Iii With Severe Dysplasia

  • Cervix Ca In Situ

  • Cin Iii

  • Cin Iii - Carcinoma In Situ Of Cervix

  • Cin Iii - Severe Dyskaryosis

  • Severe Dysplasia Of Cervix

  • Severe Dysplasia Of The Cervix Uteri

  • Squamous Intraepithelial Neoplasia, Grade Iii

  • Cervix Intraepithelial Neoplasia Grade 3 Ajcc V7

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Mus musculus LGALS7B MGD MGI:1316742