Cnot8 - CCR4-NOT transcription complex, subunit 8 Gene

Also Known as 1500015I04Rik; 1810022F04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 69125

Summary

Predicted to enable poly(A)-specific ribonuclease activity. Predicted to be involved in exonucleolytic catabolism of deadenylated mRNA and positive regulation of cell population proliferation. Predicted to act upstream of or within gene silencing by RNA and regulation of translation. Predicted to be located in nucleus. Predicted to be part of CCR4-NOT core complex. Predicted to be active in P-body. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and retina. Orthologous to human CNOT8 (CCR4-NOT transcription complex subunit 8). [provided by Alliance of Genome Resources, Apr 2022]

Cnot8 Products (5)

mRNA Protein Name
NM_001356477.2 NP_001343406.1 CCR4-NOT transcription complex subunit 8
NM_001363084.1 NP_001350013.1 CCR4-NOT transcription complex subunit 8
NM_001363085.1 NP_001350014.1 CCR4-NOT transcription complex subunit 8
NM_001363086.1 NP_001350015.1 CCR4-NOT transcription complex subunit 8
NM_026949.5 NP_081225.1 CCR4-NOT transcription complex subunit 8

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
20211142 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

CCR4-NOT transcription complex subunit 8

  • CCR4-associated factor 8

Cnot8 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Cnot8 Q9D8X5 Btg2 Mus musculus Q04211
Pull Down
20211142
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02908 CNOT8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cnot8 NCBI NCBI:9337