Pygo1 - pygopus 1 Gene

Also Known as 2600014C22Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 72135

Summary

Predicted to enable methylated histone binding activity. Involved in canonical Wnt signaling pathway. Acts upstream of or within several processes, including hematopoietic progenitor cell differentiation; protein localization to nucleus; and spermatid nucleus differentiation. Located in nucleus. Is expressed in several structures, including central nervous system; heart; male reproductive system; pancreas; and urinary system. Orthologous to human PYGO1 (pygopus family PHD finger 1). [provided by Alliance of Genome Resources, Apr 2022]

Pygo1 Products (1)

mRNA Protein Name
NM_028116.3 NP_082392.1 pygopus homolog 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21399610 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within anatomical structure development IGI
IGI: Inferred from genetic interaction
17425782 MGI
involved in canonical Wnt signaling pathway IGI
IGI: Inferred from genetic interaction
17425782 MGI
acts upstream of or within hematopoietic progenitor cell differentiation IMP
IMP: Inferred from mutant phenotype
24029230 MGI
acts upstream of or within kidney development IGI
IGI: Inferred from genetic interaction
17425782 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
15574752 MGI
acts upstream of or within protein localization to nucleus IDA
IDA: Inferred from direct assay
15574752 MGI
acts upstream of or within spermatid development IGI
IGI: Inferred from genetic interaction
23637336 MGI
acts upstream of or within spermatid nucleus differentiation IGI
IGI: Inferred from genetic interaction
23637336 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
15574752 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

pygopus homolog 1

Pygo1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
Pygo1 Q9D0P5 ebd1 Drosophila melanogaster Q9W0N9
Pull Down
21399610
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11491 PYGO1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pygo1 NCBI NCBI:26108