2. Gene
  3. Dis3 - DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease Gene

Dis3 - DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 2810028N01Rik

Gene ID: 72662 | Gene type: protein coding

About Dis3

Summary

Predicted to enable 3'-5'-exoribonuclease activity; Endonuclease activity; and guanyl-nucleotide exchange factor activity. Predicted to be involved in CUT catabolic process and rRNA catabolic process. Predicted to act upstream of or within rRNA processing. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of cytoplasmic exosome (RNase complex) and nuclear exosome (RNase complex). Is expressed in renal cortex; telencephalon ventricular layer; and thymus primordium. Orthologous to human DIS3 (DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease). [provided by Alliance of Genome Resources, Apr 2022]

Dis3 Products(3)

mRNA Protein Name
NM_001360050.1 NP_001346979.1 exosome complex exonuclease RRP44 isoform 2
NM_001360051.1 NP_001346980.1 exosome complex exonuclease RRP44 isoform 3
NM_028315.2 NP_082591.2 exosome complex exonuclease RRP44 isoform 1
Protein Preferred Names Protein Names

exosome complex exonuclease RRP44

DIS3 mitotic control homolog

protein DIS3 homolog

ribosomal RNA-processing protein 44

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-171498 gDIS3-13 Inducer 96.75% Unkown
HY-RS03778 DIS3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03779 DIS3L Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03780 DIS3L2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-173081 4"-(2-(p-Chlorophenyl)acetoxyl)spiramycin Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dis3 NCBI NCBI:22894