Insig2 - insulin induced gene 2 Gene
Also Known as Insig-2; 2900053I11Rik; C730043J18Rik
Species: Mus musculus
Gene Type: protein coding
Gene ID: 72999
Summary
Predicted to enable oxysterol binding activity. Acts upstream of or within several processes, including Cholesterol biosynthetic process; ear morphogenesis; and negative regulation of lipid biosynthetic process. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of SREBP-SCAP-Insig complex. Predicted to be active in endoplasmic reticulum. Is expressed in central nervous system; jaw bone; and retina. Orthologous to human INSIG2 (Insulin induced gene 2). [provided by Alliance of Genome Resources, Apr 2022]
Insig2 Products (5)
| mRNA | Protein | Name |
|---|---|---|
| NM_001271531.1 | NP_001258460.1 | insulin-induced gene 2 protein isoform 1 |
| NM_001271532.1 | NP_001258461.1 | insulin-induced gene 2 protein isoform 2 |
| NM_001357251.1 | NP_001344180.1 | insulin-induced gene 2 protein isoform 1 |
| NM_133748.2 | NP_598509.1 | insulin-induced gene 2 protein isoform 1 |
| NM_178082.3 | NP_835183.1 | insulin-induced gene 2 protein isoform 1 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
12242332 | MGI |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
insulin-induced gene 2 protein |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(2)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-N20666 | Canola oil | / | Unkown | |
| HY-RS06838 | INSIG2 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
Compound Screening Libraries
Virtual Screening
Customize Your Library
Drug Screening Service