Katnb1 - katanin p80 (WD40-containing) subunit B 1 Gene

Also Known as KAT; 2410003J24Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 74187

Summary

Enables dynein complex binding activity. Predicted to be involved in several processes, including microtubule Cytoskeleton organization; positive regulation of neuron projection development; and regulation of microtubule depolymerization. Predicted to act upstream of or within cell division. Located in axon and centrosome. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and primitive streak. Human ortholog(s) of this gene implicated in lissencephaly 6. Orthologous to human KATNB1 (katanin regulatory subunit B1). [provided by Alliance of Genome Resources, Apr 2022]

Katnb1 Products (1)

mRNA Protein Name
NM_028805.2 NP_083081.2 katanin p80 WD40 repeat-containing subunit B1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables dynein complex binding IDA
IDA: Inferred from direct assay
16203747 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
16203747 MGI
Cellular Component GO Annotation Evidence References Source
located in axon IDA
IDA: Inferred from direct assay
15944385 MGI
located in centrosome IDA
IDA: Inferred from direct assay
16203747 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

katanin p80 WD40 repeat-containing subunit B1

  • katanin p80 subunit B1

  • p80 katanin

Katnb1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Katnb1 Q8BG40 Katna1 Mus musculus Q9WV86
Pull Down
22325007
Intra
Katnb1 Q8BG40 Katna1 Mus musculus Q9WV86
Pull Down
28436967
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07087 KATNB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Katnb1 NCBI NCBI:10300