Slc6a19 - solute carrier family 6 (neurotransmitter transporter), member 19 Gene

Also Known as BAT1; 4632401C08Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 74338

Summary

Enables neutral amino acid transmembrane transporter activity. Acts upstream of or within neutral amino acid transport. Located in apical plasma membrane and brush border membrane. Is expressed in metanephros. Used to study Hartnup disease. Human ortholog(s) of this gene implicated in Hartnup disease and iminoglycinuria. Orthologous to human SLC6A19 (solute carrier family 6 member 19). [provided by Alliance of Genome Resources, Apr 2022]

Slc6a19 Products (2)

mRNA Protein Name
NM_001359603.1 NP_001346532.1 sodium-dependent neutral amino acid transporter B(0)AT1 isoform 2
NM_028878.4 NP_083154.1 sodium-dependent neutral amino acid transporter B(0)AT1 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables neutral L-amino acid transmembrane transporter activity IDA
IDA: Inferred from direct assay
15044460 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
17167413 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within neutral amino acid transport IDA
IDA: Inferred from direct assay
15044460 MGI
involved in neutral amino acid transport IMP
IMP: Inferred from mutant phenotype
19185582 MGI
Cellular Component GO Annotation Evidence References Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
18424768 MGI
located in brush border membrane IDA
IDA: Inferred from direct assay
17167413 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sodium-dependent neutral amino acid transporter B(0)AT1

  • solute carrier family 6 member 19

  • system B(0) neutral amino acid transporter AT1

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-156682 JNT-517 Inhibitor 99.00% Phase 3

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-B1274 Cinromide Inhibitor 99.83% Unkown
HY-162864 JX237 Inhibitor 98.84% Unkown
HY-179581 SLC6A19-IN-4 Inhibitor 99.55% Unkown
HY-158161 SLC6A19-IN-1 Inhibitor / Unkown
HY-176873 SLC6A19-IN-2 Inhibitor / Unkown
HY-179107 SLC6A19-IN-3 Inhibitor / Unkown
HY-RS13305 SLC6A19 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-179689 SLC6A19-IN-5 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc6a19 NCBI NCBI:340024