Dcstamp - dendrocyte expressed seven transmembrane protein Gene

Mus musculus

Also known as FIND; Tm7sf4; DC-STAMP; mDC-STAMP; 4833414I07Rik

Gene ID: 75766 | Gene type: protein coding

About Dcstamp

Summary

Involved in several processes, including cellular response to cytokine stimulus; myeloid leukocyte differentiation; and positive regulation of bone resorption. Located in cell surface; endoplasmic reticulum membrane; and endosome membrane. Orthologous to human DCSTAMP (dendrocyte expressed seven transmembrane protein). [provided by Alliance of Genome Resources, Apr 2022]

Dcstamp Products(5)

mRNA	Protein	Name
NM_001289506.1	NP_001276435.1	dendritic cell-specific transmembrane protein isoform 2
NM_001289508.1	NP_001276437.1	dendritic cell-specific transmembrane protein isoform 3
NM_001289512.1	NP_001276441.1	dendritic cell-specific transmembrane protein isoform 4
NM_001289513.1	NP_001276442.1	dendritic cell-specific transmembrane protein isoform 5
NM_029422.4	NP_083698.1	dendritic cell-specific transmembrane protein isoform 1

Gene Ontology

Biological Process
Cellular Component

Biological Process GO Annotation	Evidence	Reference	Source
involved in cellular response to macrophage colony-stimulating factor stimulus	IDA IDA: Inferred from direct assay	16061724	MGI
involved in cellular response to tumor necrosis factor	IDA IDA: Inferred from direct assay	16061724	MGI
involved in membrane fusion	IDA IDA: Inferred from direct assay	16061724	MGI
involved in membrane fusion	IMP IMP: Inferred from mutant phenotype	16937266	MGI
involved in myeloid dendritic cell differentiation	IDA IDA: Inferred from direct assay	17713547	MGI
involved in negative regulation of cell growth	IDA IDA: Inferred from direct assay	17713547	MGI
involved in osteoclast differentiation	IMP IMP: Inferred from mutant phenotype	15452179	MGI
acts upstream of or within osteoclast fusion	IDA IDA: Inferred from direct assay	23980096	MGI
involved in osteoclast fusion	IDA IDA: Inferred from direct assay	16061724	MGI
involved in osteoclast fusion	IMP IMP: Inferred from mutant phenotype	17164993	MGI
involved in positive regulation of bone resorption	IMP IMP: Inferred from mutant phenotype	16061724	MGI
involved in positive regulation of macrophage fusion	IDA IDA: Inferred from direct assay	16937266	MGI
acts upstream of or within positive regulation of macrophage fusion	IGI IGI: Inferred from genetic interaction	22865856	MGI
involved in positive regulation of macrophage fusion	IMP IMP: Inferred from mutant phenotype	16061724	MGI
involved in positive regulation of monocyte differentiation	IDA IDA: Inferred from direct assay	17713547	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in cell surface	IDA IDA: Inferred from direct assay	15452179	MGI
located in endoplasmic reticulum membrane	IDA IDA: Inferred from direct assay	15601667	MGI
located in endosome membrane	IDA IDA: Inferred from direct assay	18653699	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

dendritic cell-specific transmembrane protein

dentrocyte expressed seven transmembrane protein

transmembrane 7 superfamily member 4

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-180801	E8431		/	Unkown
HY-RS03590	DCSTAMP Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Dcstamp	NCBI	NCBI:81501

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