2. Gene
  3. Arhgap15 - Rho GTPase activating protein 15 Gene

Arhgap15 - Rho GTPase activating protein 15 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 5830480G12Rik

Gene ID: 76117 | Gene type: protein coding

About Arhgap15

Summary

The protein encoded by this gene is a RAC GTPase-activating protein that is regulated through its PH domain and by recruitment to the membrane. The protein accelerates hydrolysis of guanosine triphosphate to guanosine diphosphate to repress Rac activity. Knock-out of Arhgap15 function demonstrates that this gene is required to regulate multiple functions in macrophages and neutrophils. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2014]

Arhgap15 Products(4)

mRNA Protein Name
NM_001301831.1 NP_001288760.1 rho GTPase-activating protein 15 isoform 3
NM_001301832.1 NP_001288761.1 rho GTPase-activating protein 15 isoform 4
NM_001364029.1 NP_001350958.1 rho GTPase-activating protein 15 isoform 5
NM_153820.3 NP_722542.2 rho GTPase-activating protein 15 isoform 1
Protein Preferred Names Protein Names

rho GTPase-activating protein 15

rho-type GTPase-activating protein 15

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00916 ARHGAP15 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Arhgap15 NCBI NCBI:55843