Clasp2 - CLIP associating protein 2 Gene

Also Known as mKIAA0627; CLASP2beta; 1500004F14Rik; 8030404L10Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 76499

Summary

Enables microtubule binding activity. Acts upstream of or within cell migration; establishment or maintenance of cell polarity; and negative regulation of microtubule depolymerization. Located in Golgi apparatus; cell leading edge; and microtubule Cytoskeleton. Is expressed in early conceptus; nervous system; and oocyte. Orthologous to human CLASP2 (cytoplasmic linker associated protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Clasp2 Products (8)

mRNA Protein Name
NM_001081960.1 NP_001075429.1 CLIP-associating protein 2 isoform b
NM_001114347.1 NP_001107819.1 CLIP-associating protein 2 isoform c
NM_001286599.1 NP_001273528.1 CLIP-associating protein 2 isoform d
NM_001286600.1 NP_001273529.1 CLIP-associating protein 2 isoform e
NM_001286601.1 NP_001273530.1 CLIP-associating protein 2 isoform f
NM_001286602.1 NP_001273531.1 CLIP-associating protein 2 isoform g
NM_001286603.1 NP_001273532.1 CLIP-associating protein 2 isoform h
NM_029633.2 NP_083909.2 CLIP-associating protein 2 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables microtubule binding IDA
IDA: Inferred from direct assay
11290329 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
11290329 MGI
Biological Process GO Annotation Evidence References Source
involved in cell migration IGI
IGI: Inferred from genetic interaction
27378169 MGI
involved in establishment of cell polarity IGI
IGI: Inferred from genetic interaction
27378169 MGI
acts upstream of or within establishment or maintenance of cell polarity IMP
IMP: Inferred from mutant phenotype
17113391 MGI
acts upstream of or within fibroblast migration IMP
IMP: Inferred from mutant phenotype
17113391 MGI
acts upstream of microtubule depolymerization IMP
IMP: Inferred from mutant phenotype
17113391 MGI
acts upstream of or within negative regulation of microtubule depolymerization IDA
IDA: Inferred from direct assay
11290329 MGI
acts upstream of or within negative regulation of microtubule depolymerization IMP
IMP: Inferred from mutant phenotype
17113391 MGI
Cellular Component GO Annotation Evidence References Source
located in Golgi apparatus IDA
IDA: Inferred from direct assay
11290329 MGI
located in cell leading edge IDA
IDA: Inferred from direct assay
24211587 MGI
located in microtubule IDA
IDA: Inferred from direct assay
28550165 MGI
located in microtubule cytoskeleton IDA
IDA: Inferred from direct assay
11290329 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

CLIP-associating protein 2

  • CLASP2alpha

  • CLASP2gamma

  • CLIP-associating protein CLASP2

  • cytoplasmic linker-associated protein 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P0227 SHU 9119 99.83% Unkown
HY-P1208 PG-931 Agonist 99.60% Unkown
HY-RS02745 CLASP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Clasp2 NCBI NCBI:23122