Agl - amylo-1,6-glucosidase, 4-alpha-glucanotransferase Gene

Also Known as 1110061O17Rik; 9430004C13Rik; 9630046L06Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 77559

Summary

Enables glycogen debranching enzyme activity; polysaccharide binding activity; and polyubiquitin modification-dependent protein binding activity. Acts upstream of or within glycogen metabolic process. Located in cytoplasm; inclusion body; and nucleus. Is expressed in several structures, including alimentary system; central nervous system; heart; musculature; and sensory organ. Used to study glycogen storage disease III. Human ortholog(s) of this gene implicated in glycogen storage disease III. Orthologous to human AGL (amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase). [provided by Alliance of Genome Resources, Apr 2022]

Agl Products (2)

mRNA Protein Name
NM_001081326.1 NP_001074795.1 glycogen debranching enzyme isoform 1
NM_001362367.1 NP_001349296.1 glycogen debranching enzyme isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables 4-alpha-glucanotransferase activity IMP
IMP: Inferred from mutant phenotype
24613482 MGI
enables amylo-alpha-1,6-glucosidase activity IMP
IMP: Inferred from mutant phenotype
24613482 MGI
enables glycogen debranching enzyme activity IDA
IDA: Inferred from direct assay
11785984 MGI
enables polysaccharide binding IDA
IDA: Inferred from direct assay
17908927 MGI
enables polysaccharide binding IMP
IMP: Inferred from mutant phenotype
17908927 MGI
enables polyubiquitin modification-dependent protein binding IDA
IDA: Inferred from direct assay
17908927 MGI
enables polyubiquitin modification-dependent protein binding IMP
IMP: Inferred from mutant phenotype
17908927 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
15886229 MGI
Biological Process GO Annotation Evidence References Source
involved in glycogen catabolic process IMP
IMP: Inferred from mutant phenotype
24613482 MGI
acts upstream of or within glycogen metabolic process IDA
IDA: Inferred from direct assay
11785984 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
17908927 MGI
is active in cytosol IDA
IDA: Inferred from direct assay
24613482 MGI
is active in cytosol IMP
IMP: Inferred from mutant phenotype
24613482 MGI
located in inclusion body IDA
IDA: Inferred from direct assay
17908927 MGI
located in nucleus IDA
IDA: Inferred from direct assay
17908927 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glycogen debranching enzyme

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (11)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-13805 PP2 Inhibitor 99.14% Unkown
HY-13804 PP1 99.57% Unkown
HY-112720 AGL-2263 Inhibitor 98.31% Unkown
HY-13805R PP2 (Standard) Inhibitor 99.05% Unkown
HY-144584 AGL-0182-30 / Unkown
HY-RS00449 AGL Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-112350 AGL 2043 Inhibitor / Unkown
HY-P1364 Pep1-AGL Control / Unkown
HY-RS17356 Agl Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23810 Agl Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27209 Btg2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Agl NCBI NCBI:178