Hook1 - hook microtubule tethering protein 1 Gene

Also Known as azh; A930033L17Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 77963

Summary

Enables actin binding activity and microtubule binding activity. Acts upstream of or within Golgi organization; cytoplasmic microtubule organization; and manchette assembly. Located in microtubule Cytoskeleton. Is expressed in embryo; forelimb bud; spermatid; and testis. Orthologous to human HOOK1 (hook microtubule tethering protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Hook1 Products (1)

mRNA Protein Name
NM_030014.2 NP_084290.1 protein Hook homolog 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables actin binding IDA
IDA: Inferred from direct assay
14668490 MGI
enables microtubule binding IDA
IDA: Inferred from direct assay
14668490 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
14668490 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within Golgi organization IMP
IMP: Inferred from mutant phenotype
16540102 MGI
acts upstream of or within cytoplasmic microtubule organization IMP
IMP: Inferred from mutant phenotype
16540102 MGI
acts upstream of or within manchette assembly IMP
IMP: Inferred from mutant phenotype
9674995 MGI
acts upstream of or within spermatid development IMP
IMP: Inferred from mutant phenotype
12075009 MGI
Cellular Component GO Annotation Evidence References Source
located in microtubule cytoskeleton IDA
IDA: Inferred from direct assay
12075009 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein Hook homolog 1

  • abnormal spermatozoon head shape

  • hook homolog 1

  • mHK1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-N4307 Laetanine Inhibitor / Unkown
HY-168619 DNA crosslinker 6 Inhibitor / Unkown
HY-N17911 Plicatol D / Unkown
HY-RS06287 HOOK1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hook1 NCBI NCBI:51361