Srd5a1 - steroid 5 alpha-reductase 1 Gene

Also Known as S5AR 1; Srd5a-1; 0610031P22Rik; 4930435F02Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 78925

Summary

Enables 3-oxo-5-alpha-steroid 4-dehydrogenase activity. Acts upstream of or within androgen biosynthetic process. Predicted to be located in several cellular components, including cell body fiber; neuronal cell body; and perinuclear region of cytoplasm. Is expressed in alimentary system; genitourinary system; hypothalamus; and liver. Human ortholog(s) of this gene implicated in prostate Cancer and prostatic hypertrophy. Orthologous to human SRD5A1 (steroid 5 alpha-reductase 1). [provided by Alliance of Genome Resources, Apr 2022]

Srd5a1 Products (1)

mRNA Protein Name
NM_175283.3 NP_780492.2 3-oxo-5-alpha-steroid 4-dehydrogenase 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables 3-oxo-5-alpha-steroid 4-dehydrogenase activity IMP
IMP: Inferred from mutant phenotype
15249131 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within androgen biosynthetic process IMP
IMP: Inferred from mutant phenotype
15249131 MGI
involved in androgen biosynthetic process IMP
IMP: Inferred from mutant phenotype
15249131 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

3-oxo-5-alpha-steroid 4-dehydrogenase 1

  • SR type 1

  • type 1 5alpha-reductase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-152094 SRD5A1-IN-1 Inhibitor 99.82% Unkown
HY-RS13754 SRD5A1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-175719 SRD5A1-IN-2 Inhibitor / Unkown
HY-RS19076 Srd5a1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25567 Srd5a1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Srd5a1 NCBI NCBI:6715