AGMAT - agmatinase Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 79814

About AGMAT

Cytogenetic location: 1p36.21 Genomic coordinates (GRCh38): 1:15,571,699-15,585,051 (from NCBI)

This gene has 1 transcript (splice variant), 196 orthologues and 2 paralogues. Biased expression in kidney (RPKM 88.3), liver (RPKM 22.6) and 5 other tissues.

Summary

Predicted to enable agmatinase activity. Predicted to be involved in putrescine biosynthetic process from arginine, using agmatinase. Predicted to be located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

AGMAT Products (1)

mRNA Protein Name
NM_024758.5 NP_079034.3 agmatinase, mitochondrial precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables arginase activity IDA
IDA: Inferred from direct assay
36543883 GOA
enables guanidinobutyrase activity IDA
IDA: Inferred from direct assay
36543883 GOA
enables guanidinopropionase activity IDA
IDA: Inferred from direct assay
36543883 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
33961781 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

AGMAT Protein Structure

Arginase

Arginase: Arginase family (72 - 343)

  • 0
  • 100
  • 200
  • 300
  • 352 a.a.
Protein Preferred Names Protein Names

agmatinase, mitochondrial

  • AUH

AGMAT Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
AGMAT Q9BSE5 DCX Homo sapiens O43602
Anti Tag CoIP
33961781
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Moyamoya Angiopathy
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00450 AGMAT Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21475 Agmat Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27993 Agmat Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus AGMAT MGD MGI:1923236
Macaca mulatta AGMAT VGNC VGNC:99837
Canis familiaris AGMAT VGNC VGNC:37705
Rattus norvegicus AGMAT RGD RGD:1308424
Bos taurus AGMAT VGNC VGNC:25730
Felis catus AGMAT VGNC VGNC:59683
Others AGMAT NCBI