Cdk5rap3 - CDK5 regulatory subunit associated protein 3 Gene

Rattus norvegicus

Also known as C53

Gene ID: 80278 | Gene type: protein coding

About Cdk5rap3

Summary

Predicted to enable several functions, including MDM2/MDM4 family protein binding activity; NF-kappaB binding activity; and enzyme binding activity. Involved in negative regulation of cyclin-dependent protein serine/threonine kinase activity. Predicted to be located in centrosome; cytosol; and nucleolus. Predicted to be part of protein-containing complex. Predicted to colocalize with microtubule. Orthologous to human CDK5RAP3 (CDK5 regulatory subunit associated protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Cdk5rap3 Products(1)

mRNA	Protein	Name
NM_024488.2	NP_077814.2	CDK5 regulatory subunit-associated protein 3

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein-containing complex binding	IDA IDA: Inferred from direct assay	10721722	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in negative regulation of cyclin-dependent protein serine/threonine kinase activity	IDA IDA: Inferred from direct assay	10721722	RGD
involved in regulation of cyclin-dependent protein serine/threonine kinase activity	IDA IDA: Inferred from direct assay	10721722	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

CDK5 regulatory subunit-associated protein 3

CDK5 activator-binding protein C53

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02391	CDK5RAP3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Cdk5rap3	NCBI	NCBI:80279

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