PDRG1 - p53 and DNA damage regulated 1 Gene

Also Known as PDRG; C20orf126

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 81572

About PDRG1

Cytogenetic location: 20q11.21 Genomic coordinates (GRCh38): 20:31,944,337-31,952,046 (from NCBI)

This gene has 1 transcript (splice variant) and 192 orthologues. Broad expression in testis (RPKM 24.8), placenta (RPKM 9.3) and 25 other tissues.

Summary

Predicted to enable unfolded protein binding activity. Predicted to be involved in protein folding. Predicted to be located in cytoplasm. Predicted to be part of prefoldin complex. [provided by Alliance of Genome Resources, Apr 2022]

PDRG1 Products (1)

mRNA Protein Name
NM_030815.3 NP_110442.1 p53 and DNA damage-regulated protein 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25036637 GOA
Cellular Component GO Annotation Evidence References Source
part of RPAP3/R2TP/prefoldin-like complex IPI
IPI: Inferred from physical interaction
31738558 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PDRG1 Protein Structure

Prefoldin_2

Prefoldin_2: Prefoldin subunit (29 - 106)

  • 0
  • 100
  • 133 a.a.
Protein Preferred Names Protein Names

p53 and DNA damage-regulated protein 1

  • epididymis secretory sperm binding protein

PDRG1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
PDRG1 Q9NUG6 CEP76 Homo sapiens Q8TAP6
Y2H Array
32296183
Intra
PDRG1 Q9NUG6 CEP76 Homo sapiens Q8TAP6
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant PDRG1 Proteins

Cat. No. Product Name Accession Purity
HY-P76537 PDRG1 Protein, Human (His) Q9NUG6 (M1-G133) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10290 PDRG1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20076 Pdrg1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26579 Pdrg1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus PDRG1 RGD RGD:1305096
Felis catus PDRG1 VGNC VGNC:64096
Bos taurus PDRG1 VGNC VGNC:32716
Macaca mulatta PDRG1 VGNC VGNC:75808
Canis familiaris PDRG1 VGNC VGNC:44391
Mus musculus PDRG1 MGD MGI:1915809
Others PDRG1 NCBI