2. Gene
  3. Ap2a2 - adaptor related protein complex 2 subunit alpha 2 Gene

Ap2a2 - adaptor related protein complex 2 subunit alpha 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 81637 | Gene type: protein coding

About Ap2a2

Summary

Enables phosphatidylinositol binding activity. Predicted to be involved in clathrin-dependent endocytosis. Located in synaptic vesicle. Part of AP-2 adaptor complex. Orthologous to human AP2A2 (adaptor related protein complex 2 subunit alpha 2). [provided by Alliance of Genome Resources, Apr 2022]

Ap2a2 Products(1)

mRNA Protein Name
NM_031008.2 NP_112270.2 AP-2 complex subunit alpha-2
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables phosphatidylinositol binding IMP
IMP: Inferred from mutant phenotype
12086608 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
9830048 RGD
enables protein serine/threonine kinase binding IPI
IPI: Inferred from physical interaction
20802490 RGD
enables protein-containing complex binding IPI
IPI: Inferred from physical interaction
23719817 RGD
Cellular Component GO Annotation Evidence Reference Source
part of AP-2 adaptor complex IMP
IMP: Inferred from mutant phenotype
12086608 RGD
is active in synapse IDA
IDA: Inferred from direct assay
8682861 RGD
is active in synaptic vesicle EXP
EXP: Inferred from Experiment
33376223 RGD
is active in synaptic vesicle IDA
IDA: Inferred from direct assay
33376223 RGD
located in synaptic vesicle IDA
IDA: Inferred from direct assay
2072093 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

AP-2 complex subunit alpha-2

100 kDa coated vesicle protein C

adapter-related protein complex 2 alpha-2 subunit

adapter-related protein complex 2 subunit alpha-2

adaptor protein complex AP-2 subunit alpha-2

adaptor protein complex AP-2, alpha 2 subunit

adaptor-related protein co

Related Agents

Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-W923189 Neral 97.87% Unkown
HY-159931 HW161023 Inhibitor / Unkown
HY-RS00785 AP2A2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-159879 AAK1-IN-6 Inhibitor / Unkown
HY-174213 AAK1-IN-7 Inhibitor / Unkown
HY-174214 AAK1-IN-8 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ap2a2 NCBI NCBI:161