2. Gene
  3. Nup98 - nucleoporin 98 and 96 precursor Gene

Nup98 - nucleoporin 98 and 96 precursor Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 81738 | Gene type: protein coding

About Nup98

Summary

Enables nuclear localization sequence binding activity. Involved in protein import into nucleus. Located in nucleus. Part of nuclear pore nuclear basket. Human ortholog(s) of this gene implicated in T-cell acute lymphoblastic leukemia. Orthologous to human NUP98 (nucleoporin 98 and 96 precursor). [provided by Alliance of Genome Resources, Apr 2022]

Nup98 Products(1)

mRNA Protein Name
NM_031074.2 NP_112336.2 nuclear pore complex protein Nup98-Nup96 proprotein
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables nuclear localization sequence binding IDA
IDA: Inferred from direct assay
7878057 RGD
enables peptide binding IDA
IDA: Inferred from direct assay
7736573 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
7604027 RGD
Biological Process GO Annotation Evidence Reference Source
involved in protein import into nucleus IMP
IMP: Inferred from mutant phenotype
7736573 RGD
Cellular Component GO Annotation Evidence Reference Source
located in nuclear inclusion body IDA
IDA: Inferred from direct assay
11839768 RGD
located in nuclear membrane IDA
IDA: Inferred from direct assay
11839768 RGD
located in nuclear periphery IDA
IDA: Inferred from direct assay
11839768 RGD
part of nuclear pore IDA
IDA: Inferred from direct assay
7736573 RGD
part of nuclear pore nuclear basket IDA
IDA: Inferred from direct assay
11839768 RGD
located in nucleoplasm IDA
IDA: Inferred from direct assay
7736573 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nuclear pore complex protein Nup98-Nup96

98 kDa nucleoporin

nuclear pore complex protein Nup98

nucleoporin 98kDa

nucleoporin Nup98

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-119264 PRLX-93936 98.31% Phase 2
Pre-clinical Phase
Bioactive Molecules (9)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-170430 HGC652 Ligand 98.86% Unkown
HY-119264A PRLX-93936 dihydrochloride 99.83% Unkown
HY-169325 (S)-ACE-OH 99.17% Unkown
HY-180654A JWZ-8-103 hydrochloride Modulator / Unkown
HY-180654 JWZ-8-103 Modulator / Unkown
HY-141878 di-Ellipticine-RIBOTAC / Unkown
HY-141878A di-Ellipticine-RIBOTAC TFA / Unkown
HY-169355 TrimTAC1 Degrader / Unkown
HY-RS09701 NUP98 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nup98 NCBI NCBI:4928