Nup98 - nucleoporin 98 and 96 precursor Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 81738

Summary

Enables nuclear localization sequence binding activity. Involved in protein import into nucleus. Located in nucleus. Part of nuclear pore nuclear basket. Human ortholog(s) of this gene implicated in T-cell acute lymphoblastic leukemia. Orthologous to human NUP98 (nucleoporin 98 and 96 precursor). [provided by Alliance of Genome Resources, Apr 2022]

Nup98 Products (1)

mRNA Protein Name
NM_031074.2 NP_112336.2 nuclear pore complex protein Nup98-Nup96 proprotein

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables nuclear localization sequence binding IDA
IDA: Inferred from direct assay
7878057 RGD
enables peptide binding IDA
IDA: Inferred from direct assay
7736573 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
7604027 RGD
Biological Process GO Annotation Evidence References Source
involved in protein import into nucleus IMP
IMP: Inferred from mutant phenotype
7736573 RGD
Cellular Component GO Annotation Evidence References Source
located in nuclear inclusion body IDA
IDA: Inferred from direct assay
11839768 RGD
located in nuclear membrane IDA
IDA: Inferred from direct assay
11839768 RGD
located in nuclear periphery IDA
IDA: Inferred from direct assay
11839768 RGD
part of nuclear pore IDA
IDA: Inferred from direct assay
7736573 RGD
part of nuclear pore nuclear basket IDA
IDA: Inferred from direct assay
11839768 RGD
located in nucleoplasm IDA
IDA: Inferred from direct assay
7736573 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nuclear pore complex protein Nup98-Nup96

  • 98 kDa nucleoporin

  • nuclear pore complex protein Nup98

  • nucleoporin 98kDa

  • nucleoporin Nup98

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-119264 PRLX-93936 98.31% Phase 2

Pre-clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-170430 HGC652 Ligand 98.86% Unkown
HY-119264A PRLX-93936 dihydrochloride 99.83% Unkown
HY-169325 (S)-ACE-OH 99.17% Unkown
HY-180654A JWZ-8-103 hydrochloride Modulator 99.93% Unkown
HY-169355 TrimTAC1 Degrader / Unkown
HY-180654 JWZ-8-103 Modulator 98.04% Unkown
HY-141878 di-Ellipticine-RIBOTAC / Unkown
HY-141878A di-Ellipticine-RIBOTAC TFA / Unkown
HY-RS09701 NUP98 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nup98 NCBI NCBI:4928