Rab13 - RAB13, member RAS oncogene family Gene

Rattus norvegicus

Gene ID: 81756 | Gene type: protein coding

About Rab13

Summary

Enables protein kinase A catalytic subunit binding activity. Involved in several processes, including cellular response to Insulin stimulus; establishment of Sertoli cell barrier; and protein kinase A signaling. Located in insulin-responsive compartment. Orthologous to human RAB13 (RAB13, member Ras oncogene family). [provided by Alliance of Genome Resources, Apr 2022]

Rab13 Products(1)

mRNA	Protein	Name
NM_031092.2	NP_112354.1	ras-related protein Rab-13

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	23772379	RGD
enables protein kinase A catalytic subunit binding	IPI IPI: Inferred from physical interaction	23419316	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in cellular response to insulin stimulus	IMP IMP: Inferred from mutant phenotype	21041651	RGD
involved in cortical actin cytoskeleton organization	IMP IMP: Inferred from mutant phenotype	23419316	RGD
involved in establishment of Sertoli cell barrier	IMP IMP: Inferred from mutant phenotype	23419316	RGD
involved in neuron projection development	IMP IMP: Inferred from mutant phenotype	20008558	RGD
involved in protein kinase A signaling	IMP IMP: Inferred from mutant phenotype	23419316	RGD
involved in protein localization to plasma membrane	IDA IDA: Inferred from direct assay	21041651	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in insulin-responsive compartment	IDA IDA: Inferred from direct assay	21041651	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

ras-related protein Rab-13

Rab13 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	Rab13	P35286	Leprotl1	Rattus norvegicus	Q6PDU4	Pull Down	23772379
Intra	Rab13	P35286	Leprotl1	Rattus norvegicus	Q6PDU4	Y2H	23772379

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11522	RAB13 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Rab13	NCBI	NCBI:5872

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