2. Gene
  3. Smarcd1 - SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 Gene

Smarcd1 - SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Baf60a; D15Kz1

Gene ID: 83797 | Gene type: protein coding

About Smarcd1

Summary

Predicted to enable several functions, including chromatin binding activity; molecular adaptor activity; and transcription coregulator activity. Predicted to be involved in epigenetic maintenance of chromatin in transcription-competent conformation; nucleosome disassembly; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within chromatin organization and nervous system development. Part of SWI/SNF complex; nBAF complex; and npBAF complex. Is expressed in several structures, including central nervous system; dorsal root ganglion; early conceptus; genitourinary system; and retina layer. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome. Orthologous to human SMARCD1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1). [provided by Alliance of Genome Resources, Apr 2022]

Smarcd1 Products(2)

mRNA Protein Name
NM_001411993.1 NP_001398922.1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 isoform 2
NM_031842.3 NP_114030.2 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 isoform 1
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
17255092 MGI
Cellular Component GO Annotation Evidence Reference Source
part of SWI/SNF complex IDA
IDA: Inferred from direct assay
29374058 MGI
part of SWI/SNF superfamily-type complex IDA
IDA: Inferred from direct assay
24335282 MGI
part of nBAF complex IDA
IDA: Inferred from direct assay
17640523 MGI
part of npBAF complex IDA
IDA: Inferred from direct assay
17640523 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

60 kDa BRG-1/Brm-associated factor subunit A

BRG1-associated factor 60A

SWI/SNF complex 60 kDa subunit

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-177554 KB05yne 99.97% Unkown
HY-RS13412 SMARCD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Smarcd1 NCBI NCBI:6602