2. Gene
  3. Gipc1 - GIPC PDZ domain containing family, member 1 Gene

Gipc1 - GIPC PDZ domain containing family, member 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Gipc; Rgs19; Rgs19ip1

Gene ID: 83823 | Gene type: protein coding

About Gipc1

Summary

Enables PDZ domain binding activity. Predicted to be involved in several processes, including negative regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of melanin biosynthetic process; and positive regulation of transforming growth factor beta receptor signaling pathway. Predicted to act upstream of or within several processes, including cellular response to interleukin-7; endothelial cell migration; and glutamate secretion. Located in several cellular components, including brush border; cytosol; and endocytic vesicle. Orthologous to human GIPC1 (GIPC PDZ domain containing family member 1). [provided by Alliance of Genome Resources, Apr 2022]

Gipc1 Products(1)

mRNA Protein Name
NM_053341.3 NP_445793.1 PDZ domain-containing protein GIPC1
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables PDZ domain binding IPI
IPI: Inferred from physical interaction
14617818 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
14617818 RGD
Cellular Component GO Annotation Evidence Reference Source
is active in Schaffer collateral - CA1 synapse IDA
IDA: Inferred from direct assay
16819522 RGD
located in brush border IDA
IDA: Inferred from direct assay
11912251 RGD
located in endocytic vesicle IDA
IDA: Inferred from direct assay
14617818 RGD
is active in postsynapse IDA
IDA: Inferred from direct assay
16819522 RGD
is active in presynapse IDA
IDA: Inferred from direct assay
16819522 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

PDZ domain-containing protein GIPC1

GAIP C-terminus-interacting protein

GLUT1 C-terminal-binding protein

GLUT1CBP

RGS-GAIP interacting protein, C-terminus

RGS-GAIP-interacting protein

RGS19-interacting protein 1

regulator of G-protein signaling 19 interacting protein 1

synectin

Gipc1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
Gipc1 Q9Z254 Plekhg5 Rattus norvegicus Q6RFZ7
Confocal
16467373
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05435 GIPC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gipc1 NCBI NCBI:10755