ADTRP - androgen dependent TFPI regulating protein Gene

Homo sapiens

Also known as AIG1L; C6orf105; dJ413H6.1

Gene ID: 84830 | Gene type: protein coding

About ADTRP

Cytogenetic location: 6p24.1 Genomic coordinates (GRCh38): 6:11,713,523-11,778,803 (from NCBI)

This gene has 10 transcripts (splice variants), 199 orthologues and 1 paralogue. Biased expression in small intestine (RPKM 12.0), duodenum (RPKM 8.7) and 8 other tissues.

Summary

Enables hydrolase activity. Involved in several processes, including cell migration involved in sprouting angiogenesis; negative regulation of secretion by cell; and positive regulation of macromolecule metabolic process. Located in caveola and cell surface. [provided by Alliance of Genome Resources, Apr 2022]

ADTRP Products(2)

mRNA	Protein	Name
NM_001143948.2	NP_001137420.1	androgen-dependent TFPI-regulating protein isoform 1
NM_032744.4	NP_116133.1	androgen-dependent TFPI-regulating protein isoform 2

ADTRP Protein Structure

Far-17a_AIG1

0
100
200
230 a.a.

Protein Preferred Names

Protein Names

androgen-dependent TFPI-regulating protein

FAHFA hydrolase ADTRP

Related Diseases

Diseases

Alias

Nonobstructive Coronary Artery Disease

Non-Cad

Non-Obstructive Coronary Artery Disease

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00421	ADTRP Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	ADTRP	VGNC	VGNC:37680
Felis catus	ADTRP	VGNC	VGNC:102376
Mus musculus	ADTRP	MGD	MGI:1924596
Rattus norvegicus	ADTRP	RGD	RGD:1305679
Macaca mulatta	ADTRP	VGNC	VGNC:69661
Bos taurus	ADTRP	VGNC	VGNC:25702
Others	ADTRP	NCBI

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