Ngb - neuroglobin Gene

Also Known as Glnh

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 85382

Summary

Predicted to enable oxygen carrier activity. Involved in several processes, including negative regulation of hydrogen peroxide-induced cell death; response to iron ion; and visual perception. Located in mitochondrion; neuron projection; and perikaryon. Used to study transient cerebral ischemia. Biomarker of Alzheimer's disease; encephalitis; retinal ischemia; and transient cerebral ischemia. Orthologous to human NGB (neuroglobin). [provided by Alliance of Genome Resources, Apr 2022]

Ngb Products (1)

mRNA Protein Name
NM_033359.3 NP_203523.2 neuroglobin

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in cellular response to hydrogen peroxide IMP
IMP: Inferred from mutant phenotype
18083144 RGD
involved in negative regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
18083144 RGD
involved in neuron projection development IMP
IMP: Inferred from mutant phenotype
23904011 RGD
involved in positive regulation of catalytic activity IMP
IMP: Inferred from mutant phenotype
23036890 RGD
involved in response to hypoxia IEP
IEP: Inferred from expression pattern
16750520 RGD
involved in response to iron ion IEP
IEP: Inferred from expression pattern
23231908 RGD
Cellular Component GO Annotation Evidence References Source
located in perikaryon IDA
IDA: Inferred from direct assay
18509243 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

neuroglobin

  • globin h

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-12697 NGB 2904 Antagonist 99.76% Unkown
HY-12697A NGB 2904 hydrochloride Antagonist / Unkown
HY-RS05911 GTPBP4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS09274 NGB Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ngb NCBI NCBI:58157