KCNAB3 - potassium voltage-gated channel subfamily A regulatory beta subunit 3 Gene

Also Known as AKR6A9; KCNA3B; KCNA3.1B; KV-BETA-3

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 9196

About KCNAB3

Cytogenetic location: 17p13.1 Genomic coordinates (GRCh38): 17:7,921,859-7,929,856 (from NCBI)

This gene has 6 transcripts (splice variants), 246 orthologues and 16 paralogues. Broad expression in endometrium (RPKM 5.0), brain (RPKM 1.9) and 18 other tissues.

Summary

This gene encodes a member of the Potassium Channel, voltage-gated, shaker-related subfamily. The encoded protein is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. The encoded protein forms a heterodimer with the potassium voltage-gated channel, shaker-related subfamily, member 5 gene product and regulates the activity of the alpha subunit. [provided by RefSeq, May 2012]

KCNAB3 Products (1)

mRNA Protein Name
NM_004732.4 NP_004723.2 voltage-gated potassium channel subunit beta-3

KCNAB3 Protein Structure

Aldo_ket_red

Aldo_ket_red: Aldo/keto reductase family (93 - 395)

  • 0
  • 100
  • 200
  • 300
  • 404 a.a.
Protein Preferred Names Protein Names

voltage-gated potassium channel subunit beta-3

  • K(+) channel subunit beta-3

KCNAB3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
KCNAB3 O43448 PLEKHF2 Homo sapiens Q9H8W4
Y2H Prey Pooling
32296183
Intra
KCNAB3 O43448 PLEKHF2 Homo sapiens Q9H8W4
Validated Y2H
32296183
Intra
KCNAB3 O43448 PLEKHF2 Homo sapiens Q9H8W4
Y2H Array
32296183
Intra
KCNAB3 O43448 GMDS Homo sapiens O60547
Y2H Prey Pooling
32296183
Intra
KCNAB3 O43448 GMDS Homo sapiens O60547
Validated Y2H
32296183
Intra
KCNAB3 O43448 GMDS Homo sapiens O60547
Y2H Array
32296183
Intra
KCNAB3 O43448 KCNAB2 Homo sapiens Q13303
Anti Tag CoIP
33961781
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Cone-Rod Dystrophy 6

  • CORD6

  • Retinal Cone Dystrophy 2

  • Rcd2

  • Dystrophy, Cone-Rod, Type 6

  • Retinitis Pigmentosa 6

  • Progressive Cone Degeneration

  • Cone Dystrophy
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07105 KCNAB3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus KCNAB3 VGNC VGNC:30429
Canis familiaris KCNAB3 VGNC VGNC:53420
Macaca mulatta KCNAB3 VGNC VGNC:73968
Mus musculus KCNAB3 MGD MGI:1336208
Felis catus KCNAB3 VGNC VGNC:67896
Rattus norvegicus KCNAB3 RGD RGD:61830
Others KCNAB3 NCBI