Lmod2 - leiomodin 2 (cardiac) Gene

Also Known as C-Lmod

Species: Mus musculus

Gene Type: protein coding
Gene ID: 93677

Summary

Predicted to enable actin monomer binding activity and tropomyosin binding activity. Involved in actin filament polymerization and sarcomere organization. Predicted to be located in actin filament; cardiac myofibril; and sarcomere. Predicted to be active in striated muscle thin filament. Predicted to colocalize with M band. Is expressed in several structures, including central nervous system; foregut; heart; lung; and skeletal musculature. Used to study dilated cardiomyopathy. Orthologous to human LMOD2 (leiomodin 2). [provided by Alliance of Genome Resources, Apr 2022]

Lmod2 Products (1)

mRNA Protein Name
NM_053098.2 NP_444328.1 leiomodin-2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
37126682 MGI
Biological Process GO Annotation Evidence References Source
involved in actin filament polymerization IMP
IMP: Inferred from mutant phenotype
26487682 MGI
involved in sarcomere organization IMP
IMP: Inferred from mutant phenotype
27274810 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

leiomodin-2

  • cardiac leiomodin

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07723 LMOD2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lmod2 NCBI NCBI:442721