2. Gene
  3. Lmod2 - leiomodin 2 (cardiac) Gene

Lmod2 - leiomodin 2 (cardiac) Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as C-Lmod

Gene ID: 93677 | Gene type: protein coding

About Lmod2

Summary

Predicted to enable actin monomer binding activity and tropomyosin binding activity. Involved in actin filament polymerization and sarcomere organization. Predicted to be located in actin filament; cardiac myofibril; and sarcomere. Predicted to be active in striated muscle thin filament. Predicted to colocalize with M band. Is expressed in several structures, including central nervous system; foregut; heart; lung; and skeletal musculature. Used to study dilated cardiomyopathy. Orthologous to human LMOD2 (leiomodin 2). [provided by Alliance of Genome Resources, Apr 2022]

Lmod2 Products(1)

mRNA Protein Name
NM_053098.2 NP_444328.1 leiomodin-2
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
37126682 MGI
Biological Process GO Annotation Evidence Reference Source
involved in actin filament polymerization IMP
IMP: Inferred from mutant phenotype
26487682 MGI
involved in sarcomere organization IMP
IMP: Inferred from mutant phenotype
27274810 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

leiomodin-2

cardiac leiomodin

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07723 LMOD2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lmod2 NCBI NCBI:442721