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CGB7 - chorionic gonadotropin subunit beta 7 Gene

Also Known as CGB6; CG-beta-a

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 94027

About CGB7

Cytogenetic location: 19q13.33 Genomic coordinates (GRCh38): 19:49,054,274-49,057,749 (from NCBI)

This gene has 4 transcripts (splice variants), 37 orthologues and 9 paralogues. Biased expression in placenta (RPKM 5.5), skin (RPKM 1.3) and 1 other tissue.

Summary

This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 7 subunit of chorionic gonadotropin (CG). Glycoprotein Hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the Steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq, Jul 2008]

CGB7 Products (2)

mRNA	Protein	Name
NM_001385261.1	NP_001372190.1	choriogonadotropin subunit beta 7 precursor
NM_033142.2	NP_149133.1	choriogonadotropin subunit beta 7 precursor

CGB7 Protein Structure

Cys_knot

0
100
165 a.a.

Protein Preferred Names	Protein Names
choriogonadotropin subunit beta 7	chorionic gonadotropin beta 7 subunit

Recombinant CGB7 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P76820	CGB7 Protein, Human (sf9, His)	P0DN87-1 (S21-Q165)	≥ 95%, as determined by reducing SDS-PAGE.

CGB7 Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P86051	hCG beta Antibody (YA5743)	IHC-P, ICC/IF, ELISA	Human

Related Diseases

Diseases	Alias
Ectopic Pregnancy	Eccyesis Pregnancy Ectopic Pregnancy, Ectopic Ectopic Pregnancies Extrauterine Gestation Or Pregnancy Extrauterine Pregnancy Ep - [Ectopic Pregnancy] Ectopic Mole Aborted Ectopic Pregnancy Ruptured Ectopic Pregnancy
Choriocarcinoma	Chorioepithelioma
Chromosomal Triplication	Trisomy
Seminoma	Seminoma, Pure
Teratoma	Teratomas
Down Syndrome	Trisomy 21 Complete Trisomy 21 Syndrome Down'S Syndrome Trisomy 21 Syndrome Down'S Syndrome - Trisomy 21 Downs Syndrome G Trisomy 47,Xx,+21 47,Xy,+21 Trisomy G Down Syndrome, Susceptibility To Chromosome 21 Trisomy Trisomy 21 Nos Abnormal Autosomes 21
Mixed Ductal-Endocrine Carcinoma
Leydig Cell Hypoplasia Type Ii	46,Xy Disorder Of Sex Developement Due To Partial Lh Receptor Inactivation 46,Xy Disorder Of Sex Developement Due To Partial Lh Resistance 46,Xy Disorder Of Sex Developement Due To Partial Luteinizing Hormone Resistance 46,Xy Dsd Due To Partial Lh Receptor Inactivation 46,Xy Dsd Due To Partial Lh Resistance 46,Xy Dsd Due To Partial Luteinizing Hormone Resistance Leydig Cell Hypoplasia Due To Partial Lh Receptor Inactivation Leydig Cell Hypoplasia Due To Partial Lh Resistance Leydig Cell Hypoplasia Due To Partial Luteinizing Hormone Receptor Inactivation Leydig Cell Hypoplasia Due To Partial Luteinizing Hormone Resistance Leydig Cell Hypoplasia, Type Ii
Patellofemoral Pain Syndrome
Placenta Disease	Placenta Diseases Placenta Disorder Pregnancy Complications Placenta Disorders
Germinoma
Pre-Eclampsia	Preeclampsia Gestational Hypertension Hypertension Induced By Pregnancy Pre-Eclamptic Toxaemia Pregnancy Associated Hypertension Proteinuric Hypertension Of Pregnancy Hypertension, Pregnancy-Induced, Susceptibility To Preeclampsia/Eclampsia Pregnancy Toxemia Toxaemia Of Pregnancy Gestational Proteinuric Hypertension Pregnancy-Induced Hypertension Toxemia Of Pregnancy Preeclampsia, Susceptibility To Transient Hypertension Of Pregnancy Gestational [Pregnancy-Induced] Hypertension Without Significant Proteinuria Gestational Hypertension Nos Mild Proteinuric Hypertension Of Pregnancy Pih - [Pregnancy-Induced Hypertension] Pregnancy-Induced Hypertension Nos Gestational [Pregnancy-Induced] Hypertension With Significant Proteinuria Pe - [Pre-Eclampsia] Pre-Eclampsia Nos Pre-Eclamptic Nos Pregnancy Pre-Eclampsia Puerperal Pre-Eclampsia Pre-Eclampsia Toxaemia Toxaemia In Pregnancy Pet - [Pre-Eclamptic Toxaemia] Maternal Toxaemia
Smith-Lemli-Opitz Syndrome	SLOS Rsh Syndrome 7-Dehydrocholesterol Reductase Deficiency Slo Syndrome Rutledge Lethal Multiple Congenital Anomaly Syndrome Lethal Acrodysgenital Syndrome Polydactyly, Sex Reversal, Renal Hypoplasia, And Unilobar Lung Smith-Opitz-Inborn Syndrome Polydactyly, Sex Reversal, Renal Hypoplasia, And Unilobular Lung Smith Lemli Opitz Syndrome Smith-Lemli-Opitz Syndrome, Type Ii
Cryptococcosis	Cryptococcus Neoformans Infection Torulosis Busse-Buschke'S Disease Cryptococcal Infection European Cryptococcosis Torula Infection By Cryptococcus Neoformans Cryptococcosis Infection European Blastomycosis European Blastomycotic Infection European Blastomycoses Infection Torula Histolytica Infection
Neural Tube Defects	Spina Bifida Neural Tube Defect NTD Neural Tube Defects, Susceptibility To Spinal Dysraphism Spina Bifida, Susceptibility To Rachischisis Cleft Spine Open Spine Hydrocele Spinalis Neural Tube Defect Nos Sb - [Spina Bifida] Spinal Hernia Nos Spinal Fissure Nos

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02581	CGB3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS02583	CGB7 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	CGB7	MGD	MGI:96782