CGB7 - chorionic gonadotropin subunit beta 7 Gene

Homo sapiens

Also known as CGB6; CG-beta-a

Gene ID: 94027 | Gene type: protein coding

About CGB7

Cytogenetic location: 19q13.33 Genomic coordinates (GRCh38): 19:49,054,274-49,057,749 (from NCBI)

This gene has 4 transcripts (splice variants), 37 orthologues and 9 paralogues. Biased expression in placenta (RPKM 5.5), skin (RPKM 1.3) and 1 other tissue.

Summary

This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 7 subunit of chorionic gonadotropin (CG). Glycoprotein Hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the Steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq, Jul 2008]

CGB7 Products(2)

mRNA	Protein	Name
NM_001385261.1	NP_001372190.1	choriogonadotropin subunit beta 7 precursor
NM_033142.2	NP_149133.1	choriogonadotropin subunit beta 7 precursor

CGB7 Protein Structure

Cys_knot

0
100
165 a.a.

Protein Preferred Names

Protein Names

choriogonadotropin subunit beta 7

chorionic gonadotropin beta 7 subunit

Recombinant CGB7 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P76820	CGB7 Protein, Human (sf9, His)	P0DN87 (M1-Q165)	≥95%

Related Diseases

Diseases

Alias

Ectopic Pregnancy

Eccyesis	Pregnancy Ectopic
Pregnancy, Ectopic	Ectopic Pregnancies
Extrauterine Gestation Or Pregnancy	Extrauterine Pregnancy
Ep - [Ectopic Pregnancy]	Ectopic Mole
Aborted Ectopic Pregnancy	Ruptured Ectopic Pregnancy

Choriocarcinoma

Chorioepithelioma

Chromosomal Triplication

Trisomy

Seminoma

Seminoma, Pure

Teratoma

Teratomas

Down Syndrome

Trisomy 21	Complete Trisomy 21 Syndrome
Down'S Syndrome	Trisomy 21 Syndrome
Down'S Syndrome - Trisomy 21	Downs Syndrome
G Trisomy	47,Xx,+21
47,Xy,+21	Trisomy G
Down Syndrome, Susceptibility To	Chromosome 21 Trisomy
Trisomy 21 Nos	Abnormal Autosomes 21

Mixed Ductal-Endocrine Carcinoma

Leydig Cell Hypoplasia Type Ii

46,Xy Disorder Of Sex Developement Due To Partial Lh Receptor Inactivation	46,Xy Disorder Of Sex Developement Due To Partial Lh Resistance
46,Xy Disorder Of Sex Developement Due To Partial Luteinizing Hormone Resistance	46,Xy Dsd Due To Partial Lh Receptor Inactivation
46,Xy Dsd Due To Partial Lh Resistance	46,Xy Dsd Due To Partial Luteinizing Hormone Resistance
Leydig Cell Hypoplasia Due To Partial Lh Receptor Inactivation	Leydig Cell Hypoplasia Due To Partial Lh Resistance
Leydig Cell Hypoplasia Due To Partial Luteinizing Hormone Receptor Inactivation	Leydig Cell Hypoplasia Due To Partial Luteinizing Hormone Resistance
Leydig Cell Hypoplasia, Type Ii

Patellofemoral Pain Syndrome

Placenta Disease

Placenta Diseases	Placenta Disorder
Pregnancy Complications	Placenta Disorders

Germinoma

Pre-Eclampsia

Preeclampsia	Gestational Hypertension
Hypertension Induced By Pregnancy	Pre-Eclamptic Toxaemia
Pregnancy Associated Hypertension	Proteinuric Hypertension Of Pregnancy
Hypertension, Pregnancy-Induced, Susceptibility To	Preeclampsia/Eclampsia
Pregnancy Toxemia	Toxaemia Of Pregnancy
Gestational Proteinuric Hypertension	Pregnancy-Induced Hypertension
Toxemia Of Pregnancy	Preeclampsia, Susceptibility To
Transient Hypertension Of Pregnancy	Gestational [Pregnancy-Induced] Hypertension Without Significant Proteinuria
Gestational Hypertension Nos	Mild Proteinuric Hypertension Of Pregnancy
Pih - [Pregnancy-Induced Hypertension]	Pregnancy-Induced Hypertension Nos
Gestational [Pregnancy-Induced] Hypertension With Significant Proteinuria	Pe - [Pre-Eclampsia]
Pre-Eclampsia Nos	Pre-Eclamptic Nos
Pregnancy Pre-Eclampsia	Puerperal Pre-Eclampsia
Pre-Eclampsia Toxaemia	Toxaemia In Pregnancy
Pet - [Pre-Eclamptic Toxaemia]	Maternal Toxaemia

Smith-Lemli-Opitz Syndrome

SLOS	Rsh Syndrome
7-Dehydrocholesterol Reductase Deficiency	Slo Syndrome
Rutledge Lethal Multiple Congenital Anomaly Syndrome	Lethal Acrodysgenital Syndrome
Polydactyly, Sex Reversal, Renal Hypoplasia, And Unilobar Lung	Smith-Opitz-Inborn Syndrome
Polydactyly, Sex Reversal, Renal Hypoplasia, And Unilobular Lung	Smith Lemli Opitz Syndrome
Smith-Lemli-Opitz Syndrome, Type Ii

Cryptococcosis

Cryptococcus Neoformans Infection	Torulosis
Busse-Buschke'S Disease	Cryptococcal Infection
European Cryptococcosis	Torula
Infection By Cryptococcus Neoformans	Cryptococcosis Infection
European Blastomycosis	European Blastomycotic Infection
European Blastomycoses Infection	Torula Histolytica Infection

Neural Tube Defects

Spina Bifida	Neural Tube Defect
NTD	Neural Tube Defects, Susceptibility To
Spinal Dysraphism	Spina Bifida, Susceptibility To
Rachischisis	Cleft Spine
Open Spine	Hydrocele Spinalis
Neural Tube Defect Nos	Sb - [Spina Bifida]
Spinal Hernia Nos	Spinal Fissure Nos

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02583	CGB7 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	CGB7	MGD	MGI:96782