CGB7 Protein, Human (sf9, His)

CGB7 Protein, the beta subunit of human chorionic gonadotropin (hCG), is vital in pregnancy, stimulating steroid synthesis crucial for maintaining pregnancy. As a unique beta subunit, CGB7 confers specificity to hCG, playing a distinct role in reproductive physiology. Understanding CGB7's functions has potential implications for fertility treatments and maternal health, offering insights into the intricate processes of pregnancy and reproductive adaptation. CGB7 Protein, Human (sf9, His) is the recombinant human-derived CGB7 protein, expressed by Sf9 insect cells, with C-His labeled tag. The total length of CGB7 Protein, Human (sf9, His) is 165 a.a., with molecular weight of ~25 kDa.

The CGB7 Protein serves as the beta subunit of human chorionic gonadotropin (hCG), a complex glycoprotein composed of two glycosylated subunits, alpha and beta, which are non-covalently associated. The alpha subunit is identical to those found in pituitary gonadotropin hormones (LH, FSH, and TSH). Notably, the beta subunits are distinct in each of the hormones, conferring receptor and biological specificity. CGB7 plays an essential role in pregnancy and maternal adaptation, stimulating the ovaries to synthesize steroids crucial for maintaining pregnancy. It functions as a heterodimer, consisting of a common alpha chain identical in LH, FSH, TSH, and HCG, and a unique beta chain that imparts specificity to each hormone. Understanding the role of CGB7 contributes to our knowledge of reproductive physiology, with potential implications for fertility treatments and maternal health. Further exploration of CGB7's functions holds promise for enhancing our understanding of its contributions to the intricate processes of pregnancy and reproductive adaptation.

Human

Sf9 insect cells

C-His

P0DN87 (M1-Q165)

94027  [NCBI]

Approximately 25 kDa

Greater than 95% as determined by reducing SDS-PAGE

<1 EU/μg, determined by LAL method.