Copy Link Print Information

hCG beta Antibody (YA5743)

(Synonyms: CG beta; CG-beta; CgB; CGB3; CGB3_HUMAN; CGB5; CGB7; CGB7_HUMAN; CGB8; CGHB_HUMAN; Choriogonadotropin subunit beta 3; Choriogonadotropin subunit beta 7; Choriogonadotropin subunit beta; Chorionic gonadotropin beta polypeptide; Chorionic gonadotropin chain beta)
Customer Review

Based on 1 Customer Validation

hCG beta Antibody (YA5743) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to hCG beta.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG

  • Application:

    IHC-P, ICC/IF, ELISA

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • Conjugation:
    Non-conjugated
  • Experimental Validation Results for hCG beta Antibody (YA5743)
  • hCG beta Antibody (YA5743) Product Image
Size
Price
Stock
Quantity
Amount: USD 0.00
Please select quantity
or
or

* Please select Quantity before adding items.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Service
Data Download
Related Products:
Top Publications Citing

Use of MCE Products

Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
ELISA Info
ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio 1:50-200 1:50-200 1:500-5000

Product Details

Description

hCG beta Antibody (YA5743) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to hCG beta.

  • Host Mouse
  • Clonality Monoclonal
  • Species Reactivity
    Human
Immunogen

Synthesized peptide derived from human hCG β AA range: 100-165

Purification

affinity chromatography.

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Product Properties

  • Appearance

    Solution

  • Formulation

    Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • Concentration

    Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Verification Images

  • Experimental Validation Results for hCG beta Antibody (YA5743)
    Immunohistochemical analysis of paraffin-embedded human placenta using hCG beta antibody. The section was pre-treated using heat mediated antigen retrieval with EDTA (pH 9.0) for 14 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with TBST, and then probed with the primary antibody (HY-P86051, 1/200) for 30 minutes at room temperature. The detection was performed using Polymer HRP-conjugated Goat Anti-Mouse/Rabbit lgG(H&L) secondary antibody (HY-P83652). DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.

Background

  • Function

    hCG beta is a P0DN86: Beta subunit of the human chorionic gonadotropin (hCG). hCG is a complex glycoprotein composed of two glycosylated subunits alpha and beta which are non-covalently associated. The alpha subunit is identical to those in the pituitary gonadotropin hormones (LH, FSH and TSH). The beta subunits are distinct in each of the hormones and confer receptor and biological specificity. Has an essential role in pregnancy and maternal adaptation. Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy
    P0DN87: Beta subunit of the human chorionic gonadotropin (hCG). hCG is a complex glycoprotein composed of two glycosylated subunits alpha and beta which are non-covalently associated. The alpha subunit is identical to those in the pituitary gonadotropin hormones (LH, FSH and TSH). The beta subunits are distinct in each of the hormones and confer receptor and biological specificity. Has an essential role for pregnancy and maternal adaptation. Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy

  • Subcellular Localization

    P0DN86: Secreted
    P0DN87: Secreted

  • Expression


    Tissue_specificity: P0DN86: High expression in the placenta throughout pregnancy
    P0DN87: High expression in the placenta throughout pregnancy

  • Isoforms & Post-Translational Modification

    P0DN86 has 2 isomers: P0DN86-1: 17739 Da (predicted); P0DN86-2: 19053 Da (predicted).

  • Subunit

    P0DN86: Heterodimer of a common alpha chain identical in LH, FSH, TSH and HCG and a unique beta chain distinct in each of the hormones
    P0DN87: Heterodimer of a common alpha chain identical in LH, FSH, TSH and HCG and a unique beta chain distinct in each of the hormones and confers receptor and biological specificity

  • SwissProt ID

    P0DN86 / P0DN87

  • Gene ID
    1082 [NCBI] / 94027 [NCBI]
  • Synonyms

    CG beta; CG-beta; CgB; CGB3; CGB3_HUMAN; CGB5; CGB7; CGB7_HUMAN; CGB8; CGHB_HUMAN; Choriogonadotropin subunit beta 3; Choriogonadotropin subunit beta 7; Choriogonadotropin subunit beta; Chorionic gonadotropin beta polypeptide; Chorionic gonadotropin chain beta

hCG beta Antibody (YA5743) Related Classifications

MOQ
Minimum order quantity
100 mg

Get Quote In-stock

Other size
Get Quote
Please select quantity
Amount: USD 0.00

Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • 1/16

    MedChemExpress Validation
     Immunohistochemical analysis of paraffin-embedded human placenta using hCG beta antibody. The section was pre-treated using heat mediated antigen retrieval with EDTA (pH 9.0) for 14 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with TBST, and then probed with the primary antibody (HY-P86051, 1/200) for 30 minutes at room temperature. The detection was performed using Polymer HRP-conjugated Goat Anti-Mouse/Rabbit lgG(H&L) secondary antibody (HY-P83652). DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.

  • hCG beta Antibody (YA5743) Product Image
    1/16
  • Experimental Validation Results for hCG beta Antibody (YA5743)
  • hCG beta Antibody (YA5743) Product Image
  • Experimental Validation Results for hCG beta Antibody (YA5743)
    1/1
    MedChemExpress Validation
     Immunohistochemical analysis of paraffin-embedded human placenta using hCG beta antibody. The section was pre-treated using heat mediated antigen retrieval with EDTA (pH 9.0) for 14 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with TBST, and then probed with the primary antibody (HY-P86051, 1/200) for 30 minutes at room temperature. The detection was performed using Polymer HRP-conjugated Goat Anti-Mouse/Rabbit lgG(H&L) secondary antibody (HY-P83652). DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.
  • Experimental Validation Results for hCG beta Antibody (YA5743)
  • hCG beta Antibody (YA5743) Product Image
    MedChemExpress Validation

    Immunohistochemical analysis of paraffin-embedded human placenta using hCG beta antibody. The section was pre-treated using heat mediated antigen retrieval with EDTA (pH 9.0) for 14 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with TBST, and then probed with the primary antibody (HY-P86051, 1/200) for 30 minutes at room temperature. The detection was performed using Polymer HRP-conjugated Goat Anti-Mouse/Rabbit lgG(H&L) secondary antibody (HY-P83652). DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.

  • hCG beta Antibody (YA5743) Product Image IHC-P