Pgf - placental growth factor Gene

Also Known as Plgf

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 94203

Summary

Enables identical protein binding activity. Involved in several processes, including animal organ regeneration; positive regulation of angiogenesis; and positive regulation of endothelial cell proliferation. Located in extracellular space. Used to study congestive heart failure and myocardial infarction. Biomarker of diabetic retinopathy; end stage renal disease; pre-eclampsia; and status epilepticus. Human ortholog(s) of this gene implicated in several diseases, including brain ischemia; diabetic neuropathy; glioblastoma; myocardial infarction; and pancreatic endocrine carcinoma. Orthologous to human PGF (placental growth factor). [provided by Alliance of Genome Resources, Apr 2022]

Pgf Products (1)

mRNA Protein Name
NM_053595.2 NP_446047.1 placenta growth factor precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
7706320 RGD
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
7706320 RGD
Biological Process GO Annotation Evidence References Source
involved in animal organ regeneration IEP
IEP: Inferred from expression pattern
21088600 RGD
involved in cellular response to hormone stimulus IEP
IEP: Inferred from expression pattern
9400995 RGD
involved in female pregnancy IEP
IEP: Inferred from expression pattern
16131818 RGD
involved in positive regulation of angiogenesis IDA
IDA: Inferred from direct assay
21329947 RGD
involved in positive regulation of endothelial cell proliferation IMP
IMP: Inferred from mutant phenotype
9400995 RGD
involved in response to hypoxia IEP
IEP: Inferred from expression pattern
17240241 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
9400995 RGD
involved in sprouting angiogenesis IDA
IDA: Inferred from direct assay
21408222 RGD
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
17240241 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

placenta growth factor

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-12956 Dinoprost 99.84% Unkown
HY-12956A Dinoprost tromethamine salt 98.0% Unkown
HY-128428 Carboprost 99.84% Unkown
HY-116733 Tafluprost ethyl ester Agonist / Unkown

Clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Phase
HY-129397 2,3-Dinor-11beta-prostaglandin F2alpha / Phase 4
HY-101438 Darbufelone Inhibitor 99.49% Phase 3
HY-106037 PGF2α-isopropyl ester / Phase 3
HY-112284 Ebopiprant Antagonist 98.65% Phase 2

Pre-clinical Phase

Bioactive Molecules (140)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-113209 8-Isoprostaglandin F2α 99.9% Unkown
HY-12956S Dinoprost-d4 99.9% Unkown
HY-100449 AL-8810 99.00% Unkown
HY-107381 (+)-Cloprostenol Agonist 98.06% Unkown
HY-108415 Cloprostenol sodium salt Agonist 99.84% Unkown
HY-113209S 8-Isoprostaglandin F2α-d4 98.41% Unkown
HY-113246 15-keto-Prostaglandin F2a 99.2% Unkown
HY-116161A 17-Phenyl trinor PGF2α isopropyl ester 99.76% Unkown
HY-118816 11β-Prostaglandin F2α 95.0% Unkown
HY-121314 Cloprostenol 99.86% Unkown
HY-113208 13,14-Dihydro-15-keto Prostaglandin F2α 99.0% Unkown
HY-129953 9α,11β-Prostaglandin F2α 99.9% Unkown
HY-101438A Darbufelone mesylate Inhibitor 99.65% Unkown
HY-111478 Tiaprost 98.0% Unkown
HY-114656 Dihydro-PGF1α 99.9% Unkown
HY-125774S Bimatoprost acid-d4 95.25% Unkown
HY-131632 1a,1b-Dihomo prostaglandin F2α 99.9% Unkown
HY-132277S 15-Keto Bimatoprost-d5 96.65% Unkown
HY-125774 Bimatoprost acid Agonist 99.96% Unkown
HY-101235 ICI 185282 Antagonist / Unkown
HY-105953 Froxiprost / Unkown
HY-107381A (+)-Cloprostenol sodium Agonist / Unkown
HY-108415R Cloprostenol sodium salt (Standard) Agonist / Unkown
HY-111097 AF3442 Inhibitor / Unkown
HY-113208A 11β-13,14-Dihydro-15-keto Prostaglandin F2α / Unkown
HY-113208AS1 11β-13,14-Dihydro-15-keto Prostaglandin F2α-d4 / Unkown
HY-113209R 8-Isoprostaglandin F2α (Standard) / Unkown
HY-113209S2 8-Isoprostaglandin F2α-13C5 / Unkown
HY-113459S1 13,14-Dihydro-15-keto Prostaglandin F2α-d4 / Unkown
HY-113778 15-keto-17-phenyl trinor Prostaglandin F2α / Unkown
HY-113887 Prostaglandin F1β Agonist / Unkown
HY-113887A 11β-Prostaglandin F1β Control / Unkown
HY-113887S Prostaglandin F1β-d9 / Unkown
HY-113909 Dinoprost (methoxyamine) / Unkown
HY-114660 9,11-Methane-epoxy prostaglandin F1α / Unkown
HY-114687 5,7-Dihydroxy-11-ketotetranorprostanoic acid / Unkown
HY-114850 5-trans Prostaglandin F2β / Unkown
HY-114850A (5R)-Dinoprost tromethamine / Unkown
HY-114867 (15R)-Bimatoprost Control / Unkown
HY-116051 16,16-Dimethylprostaglandin F2α / Unkown
HY-116051A 16,16-Dimethylprostaglandin F2β / Unkown
HY-116161 Bimatoprost isopropyl ester / Unkown
HY-116549 Prostaglandin F2α alcohol Agonist / Unkown
HY-116591 8-Iso-15-keto prostaglandin F2β / Unkown
HY-118294 15-OH Tafluprost Control / Unkown
HY-118648 Prostaglandin F2α methyl ester Agonist / Unkown
HY-118652 Δ17-6-keto Prostaglandin F1α Agonist / Unkown
HY-120197 17-Phenyl trinor prostaglandin F2α methyl amide Inhibitor / Unkown
HY-124085 Prostaglandin F1α alcohol / Unkown
HY-125150 AL-3138 Antagonist / Unkown
HY-125396 11-Deoxyprostaglandin F2β / Unkown
HY-125626 8-iso-15-keto Prostaglandin F2α Agonist / Unkown
HY-126762 Fenprostalene / Unkown
HY-129397S 2,3-Dinor-11β-prostaglandin F2α-d9 / Unkown
HY-12956B (5R)-Dinoprost / Unkown
HY-12956S1 Dinoprost-d9 / Unkown
HY-12956S2 Dinoprost-13C5 / Unkown
HY-129764 Prostaglandin F3α Substrate / Unkown
HY-129764A (17E)-Prostaglandin F3α Control / Unkown
HY-129953A 5-trans Prostaglandin F2α / Unkown
HY-129953B 15(R)-Prostaglandin F2α / Unkown
HY-129953C 5-trans Prostaglandin F2α tromethamine / Unkown
HY-129953F Prostaglandin F2α-biotin / Unkown
HY-129953S 9α,11β-Prostaglandin F2α-d4 / Unkown
HY-129953S1 9α,11β-Prostaglandin F2α-d9 / Unkown
HY-131617 Prostaglandin F2α 1,11-lactone Control / Unkown
HY-131696 11-deoxy Prostaglandin F1α Control / Unkown
HY-131729 16-Phenoxy tetranor Prostaglandin A2 / Unkown
HY-132277 15-Keto Bimatoprost Control / Unkown
HY-136494 Fluprostenol / Unkown
HY-136627 PGF2α analogue-1 / Unkown
HY-137024 15-Keto-PGA1 Activator / Unkown
HY-137412 PGF2α 1,15-lactone / Unkown
HY-137504 20-ethyl Prostaglandin F2α / Unkown
HY-137544 16-Phenyl tetranor Prostaglandin F2α / Unkown
HY-138244 8-iso Prostaglandin F2β / Unkown
HY-139063 16-Phenoxy tetranor prostaglandin F2α / Unkown
HY-139119 Prostaglandin F2α dimethyl amide Antagonist / Unkown
HY-139121 15(R)-17-Phenyl trinor Prostaglandin F2α Agonist / Unkown
HY-139124 15(R)-15-Methyl Prostaglandin F2α Agonist / Unkown
HY-157660 15(R)-Prostaglandin F1α / Unkown
HY-158571 17-Phenoxy trinor prostaglandin F2α / Unkown
HY-158595 15(R),19(R)-Hydroxy prostaglandin F2α / Unkown
HY-158937 15(R)-15-Methyl prostaglandin F2α methyl ester Control / Unkown
HY-163376 17-Trifluoromethylphenyl trinor prostaglandin F2α ethyl amide / Unkown
HY-163784 AKR1C3-IN-14 / Unkown
HY-165587 BM-573 Modulator / Unkown
HY-172574 8-iso-17-Phenyl trinor prostaglandin F2α / Unkown
HY-175105 17-Phenoxy trinor prostaglandin F2α isopropyl ester / Unkown
HY-176011 17-Phenyl trinor prostaglandin F2α glycinamide methyl ester Agonist / Unkown
HY-178792 TGI-15 Antagonist / Unkown
HY-179367 AR-102 free acid / Unkown
HY-N12119 ent-Prostaglandin F2α / Unkown
HY-N7857 19(R)-Hydroxy-prostaglandin F2α / Unkown
HY-RS10381 PGF Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11383 Ptgfr Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W399193 PGF2α 1,9-lactone Inhibitor / Unkown
HY-W746888 17-Phenyl trinor prostaglandin F2α diethyl amide / Unkown
HY-100449A (S)-AL-8810 Antagonist / Unkown
HY-105142 M-5011 Inhibitor / Unkown
HY-112284A Ebopiprant hydrochloride Antagonist / Unkown
HY-113209S1 8-Isoprostaglandin F2α-d9 / Unkown
HY-114841 ONO 207 / Unkown
HY-116008 8-iso Prostaglandin F3α / Unkown
HY-116502 13,14-Dihydro-15-keto prostaglandin F2α isopropyl ester / Unkown
HY-116679 17-trifluoromethylphenyl trinor Prostaglandin F2α / Unkown
HY-117717 (Rac)-SC-31391 Activator / Unkown
HY-118754 13,14-Dihydro-15-keto PGF1α / Unkown
HY-118765 Ro 23-3423 / Unkown
HY-120752 CAY10509 Inhibitor / Unkown
HY-120982 (+)-15-epi Cloprostenol / Unkown
HY-124175 16-Phenoxy prostaglandin F2α ethyl amide / Unkown
HY-124209 9-keto Fluprostenol / Unkown
HY-124219 17-Phenoxy trinor prostaglandin F2α ethyl amide Agonist / Unkown
HY-126911 11-keto Fluprostenol / Unkown
HY-128550 Carboprost methyl / Unkown
HY-133941 2,3-Dinor-6-keto-prostaglandin F1α / Unkown
HY-137520 16-Phenoxy tetranor Prostaglandin F2α cyclopropyl methyl amide / Unkown
HY-137547 20-Hydroxy-PGF2α / Unkown
HY-149588 17-Trifluoromethylphenyl trinor prostaglandin F2α methyl ester / Unkown
HY-158782 5-trans Bimatoprost acid / Unkown
HY-164997 15-keto Prostaglandin F1α / Unkown
HY-168799 3-Methoxy prostaglandin F1α / Unkown
HY-168800 19(R)-Hydroxy prostaglandin F1α / Unkown
HY-169472 11-Deoxy prostaglandin F1β / Unkown
HY-172571 15(R),19(R)-Hydroxy prostaglandin F1α / Unkown
HY-172634 8-Iso-17-phenyl trinor prostaglandin F2β / Unkown
HY-175062 8-iso Prostaglandin F2α ethanolamide / Unkown
HY-175097 AL 8810 Ethyl amide / Unkown
HY-176014 17-Phenyl trinor prostaglandin F2α glycinamide / Unkown
HY-176017 2,3-Dinor fluprostenol / Unkown
HY-176096 1α-Monohomo-17-phenyl trinor Prostaglandin F2α / Unkown
HY-176833 Prostaglandin F2α diethyl amide / Unkown
HY-181444 16-Phenoxy tetranor Prostaglandin F2α methyl amide Ligand / Unkown
HY-23190 17-Trifluoromethylphenyl-13,14-dihydro trinor prostaglandin F1α / Unkown
HY-RS18329 Pgf Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24808 Pgf Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W436495 6,15-Diketo-13,14-dihydro prostaglandin F1α / Unkown
HY-W701877 Latanoprost tris(triethylsilyl) ether Control / Unkown
HY-W746889 17-Phenyl trinor prostaglandin F2α 1,15-lactone / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pgf NCBI NCBI:5228