Dinoprost (methoxyamine)
Based on 7 publication(s) in Google Scholar
Dinoprost methoxyamine is an orally active, potent prostaglandin F (PGF) receptor (FP receptor) agonist. Dinoprost methoxyamine is a luteolytic hormone produced locally in the endometrial luminal epithelium and corpus luteum (CL). Dinoprost methoxyamine plays a key role in the onset and progression of labour.
For research use only. We do not sell to patients.
- CAS No.: 101913-98-8
- Formula: C21H39NO6
- Molecular Weight:401.54
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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- References
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Publications Citing Use of MedChemExpress (MCE) Dinoprost (methoxyamine)
More- Cell Metab. 2026 Jan 9:S1550-4131(25)00546-7. [Abstract]
- Nat Commun. 2023 May 9;14(1):2668. [Abstract]
- Phytomedicine. 2025 Jul 25:143:156866. [Abstract]
- Int J Mol Sci. 2023 Apr 10;24(8):7012. [Abstract]
- ACS Pharmacol Transl Sci. 2025 Oct 4;8(11):4095-4106. [Abstract]
- Pathol Res Pract. 2026 Jun:282:156467. [Abstract]
- Fitoterapia. 2026 Mar 17.
Customer Validation & Images
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Histological Imaging/Staining
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WB
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RT-PCR
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Cell Imaging/Staining
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WB
All Endogenous Metabolite Isoforms
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Biological Activity
Chemical Information
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CAS No. 101913-98-8
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Molecular Weight 401.54
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Formula C21H39NO6
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SMILES
CON.OC(CCC/C=C\C[C@@H]1[C@H]([C@@H](C[C@@H]1O)O)/C=C/[C@@H](O)CCCCC)=O
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Synonyms
Prostaglandin F2α (methoxyamine); PGF2α (methoxyamine)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (7)
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Journal Impact Factor
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Most Recent
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Cell Metab
2026 Jan 9:S1550-4131(25)00546-7. PMID: 41519131 -
Nat Commun
2023 May 9;14(1):2668. PMID: 37160891 -
Phytomedicine
Evodiamine inhibits NLRP3 inflammasome-mediated microglial pyroptosis and promotes remyelination via SLC2A4-regulated autophagy. [Abstract]2025 Jul 25:143:156866. PMID: 40393245
Dinoprost (methoxyamine) purchased from MedChemExpress. Usage Cited in: Phytomedicine. 2025 Jul 25:143:156866. [Abstract]
Dinoprost (20 mg/kg/d for 10 days, intraperitoneally injected). Representative images of MBP and LFB staining (scale bar, 500 μm) (n = 6), and transmission electron microscopy (scale bar, 1 μm) (n = 6) in the corpus callosum region of different groups of mice.
Dinoprost (methoxyamine) purchased from MedChemExpress. Usage Cited in: Phytomedicine. 2025 Jul 25:143:156866. [Abstract]
Dinoprost (20 mg/kg/d for 10 days, intraperitoneally injected). Expression of SLC2A4 and MBP in the mouse corpus callosum determined and statistically analyzed by protein immunoblotting.
Dinoprost (methoxyamine) purchased from MedChemExpress. Usage Cited in: Phytomedicine. 2025 Jul 25:143:156866. [Abstract]
Dinoprost (20 mg/kg/d for 10 days, intraperitoneally injected). Expression of SLC2A4 and MBP in the mouse corpus callosum determined and statistically analyzed by real-time PCR.
Dinoprost (methoxyamine) purchased from MedChemExpress. Usage Cited in: Phytomedicine. 2025 Jul 25:143:156866. [Abstract]
LPS+ATP-induced pyroptosis treated with EVO (at different concentrations) and SLC2A4 inhibitor Dinoprost (PGF2α, 1 μM, 24 h) followed by eGFP-mCherry probe detection of autophagic flux (scale bar, 20 μm) and fluorescence detection of SLC2A4 (scale bar, 50 μm): LAMP1 (green), LC3B (red), and DAPI (blue) (scale bar, 50 μm).
Dinoprost (methoxyamine) purchased from MedChemExpress. Usage Cited in: Phytomedicine. 2025 Jul 25:143:156866. [Abstract]
Western blot analysis of pyroptotic proteins GSDMD, GSDMD-N, and NLRP3 inflammasome expression after LPS+ATP induced-pyroptosis, and EVO and SLC2A4 inhibitor Dinoprost (PGF2α, 1 μM, 24 h) treatment.
Dinoprost (methoxyamine) purchased from MedChemExpress. Usage Cited in: Phytomedicine. 2025 Jul 25:143:156866. [Abstract]
Expressions of autophagy-related proteins P62, Beclin1, and LC3B detected by western blot after LPS+ATP induced-pyroptosis, and EVO and SLC2A4 inhibitor PGF2α treatment.
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Int J Mol Sci
Prostaglandin F2α Regulates Adipogenesis by Modulating Extracellular Signal-Regulated Kinase Signaling in Graves' Ophthalmopathy. [Abstract]2023 Apr 10;24(8):7012. PMID: 37108173 -
ACS Pharmacol Transl Sci
Ultrasensitive Profiling of Arachidonic Acid Metabolites Based on 5‑(Diisopropylamino)amylamine Derivatization-Ultraperformance Liquid Chromatography-Tandem Mass Spectrometry. [Abstract]2025 Oct 4;8(11):4095-4106. PMID: 41262585 -
Pathol Res Pract
Prostaglandin F2α impairs skin regeneration via FP receptor-mediated oxidative stress overriding autophagic protection in fibroblasts. [Abstract]2026 Jun:282:156467. PMID: 41985369 -
Purity & Documentation
References
[1]. Hagen Thieme, et al. Endothelin antagonism: effects of FP receptor agonists prostaglandin F2alpha and fluprostenol on trabecular meshwork contractility. Invest Ophthalmol Vis Sci. 2006 Mar;47(3):938-45. [Content Brief]
[2]. Xin Wen, et al. Prostaglandin F2α Induces Goat Corpus Luteum Regression via Endoplasmic Reticulum Stress and Autophagy. Front Physiol. 2020 Sep 11;11:868. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Dinoprost (methoxyamine) Related Classifications
HY-113909 Related Classifications
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