AKR1C3-IN-14
AKR1C3-IN-14 (compound 4) is an AKR1C3 inhibitor (IC50=0.122 μM) that reduces the overproduction of androgens by inhibiting the activity of the AKR1C3 enzyme, thereby regulating hormone-mediated signaling. AKR1C3-IN-14 also plays a role in the biosynthesis of the prostaglandin PGF2α, regulating cell proliferation by affecting this pathway. AKR1C3-IN-14 can be used in the study of prostate cancer.
For research use only. We do not sell to patients.
- CAS No.: 1057882-82-2
- Formula: C21H21BrN2O4
- Molecular Weight:445.31
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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AKR1C3 0.122 μM (IC50) |
Chemical Information
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CAS No. 1057882-82-2
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Molecular Weight 445.31
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Formula C21H21BrN2O4
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SMILES
O=C(NC1=CC=C(Br)C=C1C)CN(C)CC(C2=C(O3)C(C)=C(O)C=C2)=CC3=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)