16,16-Dimethylprostaglandin F2α
16,16-Dimethylprostaglandin F2α (16,16-Dimethyl-PGF2α) is a potent analog of PGF2α (HY-12956), which exhibits similar binding potency as PGF2α does. 16,16-Dimethylprostaglandin F2α serves as a bronchoconstrictor.
For research use only. We do not sell to patients.
- CAS No.: 39746-23-1
- Formula: C22H38O5
- Molecular Weight:382.53
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:guinea pigs model[1]
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Dosage:0-0.5 μg
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Administration:iv, single dose
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Result:Inhibited histamine-induced increase in tracheal insufflation pressure.
Chemical Information
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CAS No. 39746-23-1
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Molecular Weight 382.53
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Formula C22H38O5
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SMILES
CCCCC(C)(C)[C@H](O)/C=C/[C@@H]1[C@H]([C@H](C[C@H]1O)O)C/C=C\CCCC(O)=O
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Synonyms
16,16-Dimethyl-PGF2α
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Strandberg K, et al., Bronchial effects of some prostaglandin E and F analogues. Acta Physiol Scand. 1977 Jun;100(2):172-81. [Content Brief]
[2]. Balapure AK, et al., Structural requirements for prostaglandin analog interaction with the ovine corpus luteum prostaglandin F2 alpha receptor. Implications for development of a photoaffinity probe. Biochem Pharmacol. 1989 Jul 15;38(14):2375-81. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)