39746-23-1
39746-23-1
Chemical Structure
16,16-Dimethylprostaglandin F2α
Synonym(s): 16,16-Dimethyl-PGF2α
- CAS. Nr.: 39746-23-1
- Formula:C22H38O5
- Molecular Weight:382.53
IUPAC Name: (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((R,E)-3-hydroxy-4,4-dimethyloct-1-en-1-yl)cyclopentyl)hept-5-enoic acid
InChIKey: YMRWVEHSLXJOCD-SCOYTADVSA-N
SMILES: CCCCC(C)(C)[C@H](O)/C=C/[C@@H]1[C@H]([C@H](C[C@H]1O)O)C/C=C\CCCC(O)=O
Biological Activity: 16,16-Dimethylprostaglandin F2α (16,16-Dimethyl-PGF2α) is a potent analog of PGF2α (HY-12956), which exhibits similar binding potency as PGF2α does. 16,16-Dimethylprostaglandin F2α serves as a bronchoconstrictor[1][2].
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16,16-Dimethylprostaglandin F2α | 16,16-Dimethylprostaglandin F2α (16,16-Dimethyl-PGF2α) is a potent analog of PGF2α (HY-12956), which exhibits similar binding potency as PGF2α does. 16,16-Dimethylprostaglandin F2α serves as a bronchoconstrictor. | |||||||||||||||||||||
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References
- [1]. Strandberg K, et al., Bronchial effects of some prostaglandin E and F analogues. Acta Physiol Scand. 1977 Jun;100(2):172-81. [Content Brief]
- [2]. Balapure AK, et al., Structural requirements for prostaglandin analog interaction with the ovine corpus luteum prostaglandin F2 alpha receptor. Implications for development of a photoaffinity probe. Biochem Pharmacol. 1989 Jul 15;38(14):2375-81. [Content Brief]
Keywords
