1. GPCR/G Protein
  2. Prostaglandin Receptor
  3. Cloprostenol isopropyl ester

Cloprostenol isopropyl ester 

Cat. No.: HY-100571
Handling Instructions

Cloprostenol isopropyl ester, a prostaglandin F2α analogs, is the intermediate of (+)-Cloprostenol (HY-107381). Cloprostenol isopropyl ester is a FP receptor agonist with a Ki value of 28 nM.

For research use only. We do not sell to patients.

Cloprostenol isopropyl ester Chemical Structure

Cloprostenol isopropyl ester Chemical Structure

CAS No. : 157283-66-4

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Description

Cloprostenol isopropyl ester, a prostaglandin F2α analogs, is the intermediate of (+)-Cloprostenol (HY-107381). Cloprostenol isopropyl ester is a FP receptor agonist with a Ki value of 28 nM[1][2].

In Vivo

Cloprostenol isopropyl ester (25 μg/kg; i.p.; daily, for 4 weeks; male mice) induces changes in the evolution of the spermatogenesis and spermiogenesis[1].
Cloprostenol isopropyl ester (1 μg, 30 μL; injected into the eye; for 2, 4 and 6 h) causes pupil constriction in the cat. Cloprostenol isopropyl ester has an efficacious ocular hypotensive in the lasered monkey[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male mice (50–80 days)[1]
Dosage: 25 μg/kg
Administration: Intraperitoneal injection; daily, for 4 weeks
Result: Stimulated the androgen synthesis in a time-dependent manner.
Molecular Weight

466.99

Formula

C25H35ClO6

CAS No.
SMILES

ClC1=CC=CC(OC[[email protected]](O)/C=C/[[email protected]@H]2[[email protected]]([[email protected]](C[[email protected]]2O)O)C/C=C\CCCC(OC(C)C)=O)=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Product Name:
Cloprostenol isopropyl ester
Cat. No.:
HY-100571
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