157283-66-4
157283-66-4
Chemical Structure
Cloprostenol isopropyl ester
- CAS No.: 157283-66-4
- Formula:C25H35ClO6
- Molecular Weight:466.99
IUPAC Name: isopropyl (Z)-7-((1R,2R,3R,5S)-2-((R,E)-4-(3-chlorophenoxy)-3-hydroxybut-1-en-1-yl)-3,5-dihydroxycyclopentyl)hept-5-enoate
InChIKey: OCNSAYQJDKJOLH-AHTXBMBWSA-N
SMILES: ClC1=CC=CC(OC[C@H](O)/C=C/[C@@H]2[C@H]([C@H](C[C@H]2O)O)C/C=C\CCCC(OC(C)C)=O)=C1
Biological Activity: Cloprostenol isopropyl ester, a prostaglandin F2α analogs, is the intermediate of (+)-Cloprostenol (HY-107381). Cloprostenol isopropyl ester is a FP receptor agonist with a Ki value of 28 nM[1][2].
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Cloprostenol isopropyl ester | 98.0% | Cloprostenol isopropyl ester, a prostaglandin F2α analogs, is the intermediate of (+)-Cloprostenol (HY-107381). Cloprostenol isopropyl ester is a FP receptor agonist with a Ki value of 28 nM. | ||||||||||||||||||||
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References
- [1]. Sava A, et, al. Electron microscopic aspects of the effects of certain prostaglandin analogs on mouse testes. Rom J Morphol Embryol. 2015;56(2 Suppl):771-5. [Content Brief]
- [2]. Hellberg MR, et, al. Identification and characterization of the ocular hypotensive efficacy of travoprost, a potent and selective FP prostaglandin receptor agonist, and AL-6598, a DP prostaglandin receptor agonist. Surv Ophthalmol. 2002 Aug;47 Suppl 1:S13-33. [Content Brief]
Keywords
