Met-AMS
Met-AMS (Compound 50) is a sulfonamide analog of methionyl-adenylate (Met-AMP) and an inhibitor of isoleucyl-tRNA synthetase (IleRS) with an IC50 of 7 nM.
For research use only. We do not sell to patients.
- CAS No.: 560071-70-7
- Formula: C15H23N7O7S2
- Molecular Weight:477.52
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| PBMC | IC50 |
0.5 μM
Compound: MetSA
|
Immunosuppressive activity against human PBMC assessed as inhibition of allogenic mixed lymphocyte reaction
Immunosuppressive activity against human PBMC assessed as inhibition of allogenic mixed lymphocyte reaction
|
[PMID: 18438987] |
Chemical Information
-
CAS No. 560071-70-7
-
Molecular Weight 477.52
-
Formula C15H23N7O7S2
-
SMILES
O[C@H]1[C@@H](O)[C@H](N2C=NC3=C(N)N=CN=C32)O[C@@H]1COS(=O)(NC([C@H](CCSC)N)=O)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)