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Baricitinib phosphate

(別名: LY3009104 phosphate; INCB028050 phosphate)
78 Cited Publications
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Based on 78 publication(s) in Google Scholar

Baricitinib phosphate (LY3009104 phosphate; INCB028050 phosphate) is a selective orally bioavailable JAK1/JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM, respectively.

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  • 純度: 99.97%
  • CAS 番号: 1187595-84-1
  • 分子式: C16H20N7O6PS
  • 分子量:469.41
  • 保管条件:

    4°C, sealed storage, away from moisture

    * In solvent : -80°C, 1 year; -20°C, 6 months (sealed storage, away from moisture)

  • Baricitinib phosphate Chemical Structure
  • Experimental Validation Results for Baricitinib phosphate
  • Experimental Validation Results for Baricitinib phosphate
  • Experimental Validation Results for Baricitinib phosphate
  • Baricitinib phosphate Chemical Structure
    Baricitinib phosphate 構造式
  • Experimental Validation Results for Baricitinib phosphate
  • Experimental Validation Results for Baricitinib phosphate
  • Experimental Validation Results for Baricitinib phosphate
CAS 番号: 1187595-84-1
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  • Baricitinib phosphate Chemical Structure
    Baricitinib phosphate Chemical Structure
    1/16
  • 1/16

    Baricitinib phosphate purchased from MedChemExpress. Usage Cited in: RSC Adv. 2018 Jun 13;8(38):21534-21540. [Abstract]

    Customer Validation
     M14 and A2058 cells are treated with IFN-γ (10 ng/mL) after Lac (100 μg/mL) or baricitinib (0.5 μM) for the indicated times. Whole cell lysates are subjected to western blotting.

  • 1/16

    Baricitinib phosphate purchased from MedChemExpress. Usage Cited in: University of Toyama. 2018, Nov.

    Customer Validation
     Western analysis of pJAK2, JAK2, pSTAT1, STAT1 and IRF1 protein in M14 and A2058 cells treated with IFN-g (10 ng/mL) after Lac (100 μg/mL) or baricitinib (0.5 μM) for the indicated times.

  • 1/16

    Baricitinib phosphate purchased from MedChemExpress. Usage Cited in: PLoS One. 2017 Jul 14;12(7):e0181126. [Abstract]

    Customer Validation
     An activator of Stat3, colivelin (0.1 or 1 µM), rescued Baricitinib-induced RANKL down-regulation in osteoblast cultures.

  • Baricitinib phosphate