country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

製品番号: HY-14312

Copy Link Print Information

A85380

A 85380 is a novel, high affinity neuronal nicotinic acetylcholine receptor (nAChR) agonist. A 85380 exhibits selectivity for the α4β2 nAChR subtypes. A 85380 has a broad-spectrum analgesic profile.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 161416-98-4
分子式: C₉H₁₂N₂O
分子量:164.20

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

A85380 構造式

CAS 番号: 161416-98-4

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Cellular Effect

Cell Line	Type	Value	Description	References
IMR-32	EC₅₀	0.7 μM Compound: 2, A-85380	Functional activation of human sympathetic ganglionic type nAChRs in IMR-32 cells containing alpha-3 subtype Functional activation of human sympathetic ganglionic type nAChRs in IMR-32 cells containing alpha-3 subtype	[PMID: 9484491]
IMR-32	EC₅₀	0.7 μM Compound: 4a	Ability to stimulate Rb+ efflux from human IMR-32 cell preparations containing human alpha3-betaX receptors Ability to stimulate Rb+ efflux from human IMR-32 cell preparations containing human alpha3-betaX receptors	[PMID: 8632405]
K177 cell line	EC₅₀	0.68 μM Compound: 4a	Ability to stimulate Rb+ efflux from human K177 cell preparations containing human alpha4-beta2 receptors Ability to stimulate Rb+ efflux from human K177 cell preparations containing human alpha4-beta2 receptors	[PMID: 8632405]
K177 cell line	EC₅₀	0.7 μM Compound: 2, A-85380	Compound was evaluated for functional activation to [86Rb+] efflux from human K177 cells expressing recombinant alpha4-beta2 receptors. Compound was evaluated for functional activation to [86Rb+] efflux from human K177 cells expressing recombinant alpha4-beta2 receptors.	[PMID: 9484491]
Oocyte	EC₅₀	8.9 μM Compound: 2, A-85380	Compound was evaluated for functional activation from channel currents at human Nicotinic acetylcholine receptor alpha-7 expressed in oocytes. Compound was evaluated for functional activation from channel currents at human Nicotinic acetylcholine receptor alpha-7 expressed in oocytes.	[PMID: 9484491]

化学情報

CAS 番号 161416-98-4
分子量 164.20
分子式 C₉H₁₂N₂O
SMILES

C1(OC[C@@H]2CCN2)=CN=CC=C1
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (266 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Sullivan J P, et al. A-85380 [3-(2 (S)-azetidinylmethoxy) pyridine]: in vitro pharmacological properties of a novel, high affinity α4β2 nicotinic acetylcholine receptor ligand[J]. Neuropharmacology, 1996, 35(6): 725-734.

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

お問い合わせ在庫あり

Other size

お問い合わせ