Chrolactomycin
Chrolactomycin is found in the strain of Streptomyces sp. 569N-3. The IC50 of Chrolactomycin for ACHN, A431, McF-7 and T24 cells are 1.2 μM, 1.6 μM, 0.69 μM and 0.45 μM, respectively. Chrolactomycin has only anti-Gram-positive bacteria activity with the MIC of 5.2-10.4 μg/mL.
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- CAS 番号: 227606-82-8
- 分子式: C24H32O7
- 分子量:432.51
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A-431 | IC50 |
0.5 μM
Compound: 10
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Inhibition of human telomerase isolated from human A431 cellular extracts after 30 mins by TRAP assay
Inhibition of human telomerase isolated from human A431 cellular extracts after 30 mins by TRAP assay
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[PMID: 24053596] |
| A-431 | IC50 |
0.5 μM
Compound: Chrolactomycin
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Inhibition of telomerase extracted from human A431 cells after 30 mins by TRAP assay
Inhibition of telomerase extracted from human A431 cells after 30 mins by TRAP assay
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10.1039/C0MD00241K |
化学情報
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CAS 番号 227606-82-8
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分子量 432.51
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分子式 C24H32O7
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SMILES
CO[C@@]12[C@]3([H])[C@@]4(OC2=O)[C@](CCC[C@H](C[C@H]([C@@](C(C1=O)=C)([H])O3)C)C)([H])C=C([C@H](C4)C)C(O)=O
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Structure Classification
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Initial Source
Streptomyces
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Chrolactomycin 関連分類
HY-N14056 関連分類
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