HDAC6-IN-43
HDAC6-IN-43 (compound 26) is a potent HDAC inhibitor. HDAC6-IN-43 effectively inhibits several HDACs, notably HDAC1, HDAC2, and HDAC6 (IC50 < 150 nM), displaying a particularly high sensitivity towards HDAC6 (IC50 = 11 nM). HDAC6-IN-43 can be used for the research of autosomal dominant polycystic kidney disease (ADPKD).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 3037978-19-8
- 分子式: C21H24N2O4S
- 分子量:400.49
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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HDAC6 11 ± 1 nM (IC50) |
HDAC2 105 ± 5 nM (IC50) |
HDAC1 111 ± 5 nM (IC50) |
HDAC8 15404 ± 99 nM (IC50) |
HDAC6-IN-43 (compound 26) significantly inhibits Madin-Darby canine kidney (MDCK) cell growth and proliferation by upregulating the acetylation of α-tubulin levels[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 3037978-19-8
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分子量 400.49
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分子式 C21H24N2O4S
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SMILES
COC1=C(OCCCCCCC(NO)=O)C=C(C2=NC3=CC=CC=C3S2)C=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
HDAC6-IN-43 関連分類
HY-161524 関連分類
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