3037978-19-8
3037978-19-8
Chemical Structure
HDAC6-IN-43
- CAS No.: 3037978-19-8
- Formula:C21H24N2O4S
- Molecular Weight:400.49
InChIKey: YQNFTLWFHLMMFV-UHFFFAOYSA-N
SMILES: COC1=C(OCCCCCCC(NO)=O)C=C(C2=NC3=CC=CC=C3S2)C=C1
Biological Activity: HDAC6-IN-43 (compound 26) is a potent HDAC inhibitor. HDAC6-IN-43 effectively inhibits several HDACs, notably HDAC1, HDAC2, and HDAC6 (IC50 < 150 nM), displaying a particularly high sensitivity towards HDAC6 (IC50 = 11 nM). HDAC6-IN-43 can be used for the research of autosomal dominant polycystic kidney disease (ADPKD)[1].
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HDAC6-IN-43 | HDAC6-IN-43 (compound 26) is a potent HDAC inhibitor. HDAC6-IN-43 effectively inhibits several HDACs, notably HDAC1, HDAC2, and HDAC6 (IC50 < 150 nM), displaying a particularly high sensitivity towards HDAC6 (IC50 = 11 nM). HDAC6-IN-43 can be used for the research of autosomal dominant polycystic kidney disease (ADPKD). | |||||||||||||||||||||
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References
Keywords
