Hydroxymethyl dasatinib
Hydroxymethyl dasatinib (M24), a benzylhydroxy metabolite of Dasatinib (HY-10181), exhibits an IC50 of 46.7nM in K562 CML cells.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.92%
- CAS 番号: 910297-58-4
- 分子式: C22H26ClN7O3S
- 分子量:504.00
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
化学情報
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CAS 番号 910297-58-4
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性状 Solid
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分子量 504.00
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分子式 C22H26ClN7O3S
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Color White to light yellow
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SMILES
O=C(NC1=C(C=CC=C1Cl)CO)C2=CN=C(S2)NC3=CC(N4CCN(CC4)CCO)=NC(C)=N3
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 125 mg/mL (248.02 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
純度とドキュメンテーション
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データシート (268 KB)
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SDS (784 KB)
- English - EN (784 KB)
- Français - FR (784 KB)
- Deutsch - DE (784 KB)
- Norwegian - NO (784 KB)
- Español - ES (784 KB)
- Swedish - SV (784 KB)
- Italian - IT (784 KB)
- Portuguese - PT (784 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9841 mL | 9.9206 mL | 19.8413 mL | 49.6032 mL |
| 5 mM | 0.3968 mL | 1.9841 mL | 3.9683 mL | 9.9206 mL | |
| 10 mM | 0.1984 mL | 0.9921 mL | 1.9841 mL | 4.9603 mL | |
| 15 mM | 0.1323 mL | 0.6614 mL | 1.3228 mL | 3.3069 mL | |
| 20 mM | 0.0992 mL | 0.4960 mL | 0.9921 mL | 2.4802 mL | |
| 25 mM | 0.0794 mL | 0.3968 mL | 0.7937 mL | 1.9841 mL | |
| 30 mM | 0.0661 mL | 0.3307 mL | 0.6614 mL | 1.6534 mL | |
| 40 mM | 0.0496 mL | 0.2480 mL | 0.4960 mL | 1.2401 mL | |
| 50 mM | 0.0397 mL | 0.1984 mL | 0.3968 mL | 0.9921 mL | |
| 60 mM | 0.0331 mL | 0.1653 mL | 0.3307 mL | 0.8267 mL | |
| 80 mM | 0.0248 mL | 0.1240 mL | 0.2480 mL | 0.6200 mL | |
| 100 mM | 0.0198 mL | 0.0992 mL | 0.1984 mL | 0.4960 mL |
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